Abstract：
BACKGROUND: The efficacy and safety of cuffed endotracheal tubes (ETTs) in neonates are still unclear, this study aimed to assess the efficacy of cuffed versus uncuffed ETTs in neonate undergoing noncardiac surgeries.
METHODS: Neonates scheduled for noncardiac surgeries were randomized into two groups according to the type of airway device during general anesthesia: cuffed ETT group (n = 60) and the uncuffed ETT group (n = 60). The primary outcome was the incidence of ETT exchange to find the appropriate ETT. Other outcomes included: duration of intubation, lung ultrasound score, and incidence of postoperative complications (croup, wheezes, hypoxia, etc.).
RESULTS: The frequency of ETT exchange was lower in the cuffed ETT group compared to the uncuffed one {1 (1.7%) vs. 28 (46.7%), p = .0001; relative risk [95% confidence interval]: 0.54 [0.43-0.69]}. Postoperative adverse events were comparable between both groups except for significantly higher post extubation croup in the uncuffed ETT group compared to the cuffed ETT {10 (16.7%) vs. 3(5%), p value = .04, relative risk (95% confidence interval): 1.14 (1-1.29)}.
CONCLUSIONS: In full term neonates undergoing noncardiac surgeries, the use of cuffed ETT was associated with less need to tracheal tube exchange and less incidence of postoperative croup, without increasing the postoperative respiratory complications compared to uncuffed ETT.
METHODS: Neonates scheduled for noncardiac surgeries were randomized into two groups according to the type of airway device during general anesthesia: cuffed ETT group (n = 60) and the uncuffed ETT group (n = 60). The primary outcome was the incidence of ETT exchange to find the appropriate ETT. Other outcomes included: duration of intubation, lung ultrasound score, and incidence of postoperative complications (croup, wheezes, hypoxia, etc.).
RESULTS: The frequency of ETT exchange was lower in the cuffed ETT group compared to the uncuffed one {1 (1.7%) vs. 28 (46.7%), p = .0001; relative risk [95% confidence interval]: 0.54 [0.43-0.69]}. Postoperative adverse events were comparable between both groups except for significantly higher post extubation croup in the uncuffed ETT group compared to the cuffed ETT {10 (16.7%) vs. 3(5%), p value = .04, relative risk (95% confidence interval): 1.14 (1-1.29)}.
CONCLUSIONS: In full term neonates undergoing noncardiac surgeries, the use of cuffed ETT was associated with less need to tracheal tube exchange and less incidence of postoperative croup, without increasing the postoperative respiratory complications compared to uncuffed ETT.
摘要：
背景：新生儿使用套箍气管导管（ETTs）的疗效和安全性尚不清楚，本研究旨在评估在接受非心脏手术的新生儿中,袖口ETT与无袖口ETT的疗效.
方法：根据全身麻醉期间气道装置的类型，将计划进行非心脏手术的新生儿随机分为两组：袖口ETT组（n=60）和无袖口ETT组（n=60）。主要结果是ETT交换的发生率，以找到合适的ETT。其他结果包括：插管持续时间，肺超声评分,和术后并发症的发生率(臀部，喘息,缺氧,等。).
结果：袖口ETT组的ETT交换频率低于无袖口组{1(1.7%)与28（46.7%），p=0.0001；相对风险[95%置信区间]：0.54[0.43-0.69]}。两组之间的术后不良事件具有可比性，除了与带袖口的ETT相比，无袖口的ETT组的拔管后臀部明显更高{10(16.7%)与3（5%），p值=.04，相对风险（95%置信区间）：1.14（1-1.29）}。
结论：在接受非心脏手术的足月新生儿中，使用带袖口的ETT与较少需要更换气管导管和较少的术后臀部的发生率相关。与未翻盖的ETT相比，不会增加术后呼吸系统并发症。
方法：根据全身麻醉期间气道装置的类型，将计划进行非心脏手术的新生儿随机分为两组：袖口ETT组（n=60）和无袖口ETT组（n=60）。主要结果是ETT交换的发生率，以找到合适的ETT。其他结果包括：插管持续时间，肺超声评分,和术后并发症的发生率(臀部，喘息,缺氧,等。).
结果：袖口ETT组的ETT交换频率低于无袖口组{1(1.7%)与28（46.7%），p=0.0001；相对风险[95%置信区间]：0.54[0.43-0.69]}。两组之间的术后不良事件具有可比性，除了与带袖口的ETT相比，无袖口的ETT组的拔管后臀部明显更高{10(16.7%)与3（5%），p值=.04，相对风险（95%置信区间）：1.14（1-1.29）}。
结论：在接受非心脏手术的足月新生儿中，使用带袖口的ETT与较少需要更换气管导管和较少的术后臀部的发生率相关。与未翻盖的ETT相比，不会增加术后呼吸系统并发症。
