关键词: diagnostics elimination infestations neglected tropical diseases prevention scabies treatment

来  源:   DOI:10.1111/ijd.17327

Abstract:
Scabies, caused by the Sarcoptes scabiei var hominis mite burrowing into the skin, is a highly contagious disease characterized by intense nocturnal itching. Its global impact is considerable, affecting more than 200 million individuals annually and posing significant challenges to healthcare systems worldwide. Transmission occurs primarily through direct skin-to-skin contact, contributing to its widespread prevalence and emergence as a substantial public health concern affecting large populations. This review presents consensus-based clinical practice guidelines for diagnosing and managing scabies, developed through the fuzzy Delphi method by dermatology, parasitology, pediatrics, pharmacology, and public health experts. The presence of burrows containing adult female mites, their eggs, and excreta is the diagnostic hallmark of scabies. Definitive diagnosis typically involves direct microscopic examination of skin scrapings obtained from these burrows, although dermoscopy has become a diagnostic tool in clinical practice. Treatment modalities encompass topical agents, such as permethrin, balsam of Peru, precipitated sulfur, and benzyl benzoate. In cases where topical therapy proves inadequate or in instances of crusted scabies, oral ivermectin is recommended as a systemic treatment option. This comprehensive approach addresses the diagnostic and therapeutic challenges associated with scabies, optimizing patient care, and management outcomes.
摘要:
镰刀菌,是由沙科克人螨侵入皮肤引起的,是一种高度传染性疾病,以强烈的夜间瘙痒为特征。它的全球影响是相当大的,每年影响超过2亿人,对全球医疗保健系统构成重大挑战。传播主要通过皮肤与皮肤的直接接触发生,导致其广泛流行并成为影响大量人群的重大公共卫生问题。这篇综述提出了基于共识的临床实践指南,用于诊断和管理sc疮。通过皮肤科的模糊德尔菲法开发,寄生虫学,儿科,药理学,和公共卫生专家。存在含有成年雌性螨虫的洞穴,他们的鸡蛋,而排泄物是疮的诊断标志.明确的诊断通常涉及从这些洞穴中获得的皮肤刮屑的直接显微镜检查,尽管皮肤镜检查已成为临床实践中的诊断工具。治疗方式包括外用药物,如氯菊酯,秘鲁香脂,沉淀硫,和苯甲酸苄酯。在局部治疗证明不充分或结痂的情况下,口服伊维菌素被推荐作为全身治疗选择.这种全面的方法解决了与sc疮相关的诊断和治疗挑战,优化患者护理,和管理成果。
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