PDF(Pubmed)
Abstract：
UNASSIGNED: This study investigated the distribution of fundus tessellation density (FTD) in a Chinese pediatric population and its potential in reflecting early myopic maculopathy (tessellated fundus).
UNASSIGNED: Participants were enrolled from kindergartens, primary schools, and middle schools, with cluster sampling in Shanghai, China. A series of ophthalmic examinations was conducted. Based on fundus photograph, FTD was quantitatively assessed using an artificial intelligence algorithm, and tessellated fundus was diagnosed by well-trained ophthalmologists.
UNASSIGNED: A total of 14,234 participants aged four to 18 years were included, with 7421 boys (52.1%). Tessellated fundus was observed in 2200 (15.5%) participants. The median of FTD was 0.86% (range 0.0-42.1%). FTD increased with age and axial length. In the logistics regression, larger FTD was independently associated with tessellated fundus (P < 0.001). The area under curves of receiver operating characteristic curve for categorizing tessellated fundus using FTD was 0.774, and the cutoff point of FTD was 2.22%.
UNASSIGNED: The density of fundus tessellation was consistent with the severity of myopia. FTD could help diagnose the early stage of myopic maculopathy, tessellated fundus, providing a new pattern for myopia screening and detection of early myopic fundus changes.
UNASSIGNED: Quantification of fundus tessellation with artificial intelligence could help detect early myopic maculopathy.
UNASSIGNED: Participants were enrolled from kindergartens, primary schools, and middle schools, with cluster sampling in Shanghai, China. A series of ophthalmic examinations was conducted. Based on fundus photograph, FTD was quantitatively assessed using an artificial intelligence algorithm, and tessellated fundus was diagnosed by well-trained ophthalmologists.
UNASSIGNED: A total of 14,234 participants aged four to 18 years were included, with 7421 boys (52.1%). Tessellated fundus was observed in 2200 (15.5%) participants. The median of FTD was 0.86% (range 0.0-42.1%). FTD increased with age and axial length. In the logistics regression, larger FTD was independently associated with tessellated fundus (P < 0.001). The area under curves of receiver operating characteristic curve for categorizing tessellated fundus using FTD was 0.774, and the cutoff point of FTD was 2.22%.
UNASSIGNED: The density of fundus tessellation was consistent with the severity of myopia. FTD could help diagnose the early stage of myopic maculopathy, tessellated fundus, providing a new pattern for myopia screening and detection of early myopic fundus changes.
UNASSIGNED: Quantification of fundus tessellation with artificial intelligence could help detect early myopic maculopathy.
摘要：
■这项研究调查了中国儿科人群中眼底镶嵌密度（FTD）的分布及其在反映早期近视性黄斑病变（镶嵌眼底）中的潜力。
■参与者从幼儿园注册，小学,和中学，在上海进行整群抽样，中国。进行了一系列的眼科检查。根据眼底照片,FTD使用人工智能算法进行定量评估，并且由训练有素的眼科医生诊断出镶嵌的眼底。
■总共14,234名4至18岁的参与者被包括在内，有7421名男孩(52.1%)。2200名（15.5％）参与者观察到镶嵌的眼底。FTD的中位数为0.86%(范围为0.0-42.1%)。FTD随年龄和轴向长度而增加。在物流回归中，较大的FTD与网格状眼底独立相关(P<0.001)。使用FTD对细分眼底进行分类的受试者工作特征曲线的曲线下面积为0.774，FTD的截止点为2.22％。
■眼底细分的密度与近视的严重程度一致。FTD可以帮助诊断近视性黄斑病变的早期阶段，镶嵌眼底，为近视筛查和早期发现近视眼底改变提供了新的模式。
■用人工智能量化眼底镶嵌可以帮助发现早期近视性黄斑病变。
■参与者从幼儿园注册，小学,和中学，在上海进行整群抽样，中国。进行了一系列的眼科检查。根据眼底照片,FTD使用人工智能算法进行定量评估，并且由训练有素的眼科医生诊断出镶嵌的眼底。
■总共14,234名4至18岁的参与者被包括在内，有7421名男孩(52.1%)。2200名（15.5％）参与者观察到镶嵌的眼底。FTD的中位数为0.86%(范围为0.0-42.1%)。FTD随年龄和轴向长度而增加。在物流回归中，较大的FTD与网格状眼底独立相关(P<0.001)。使用FTD对细分眼底进行分类的受试者工作特征曲线的曲线下面积为0.774，FTD的截止点为2.22％。
■眼底细分的密度与近视的严重程度一致。FTD可以帮助诊断近视性黄斑病变的早期阶段，镶嵌眼底，为近视筛查和早期发现近视眼底改变提供了新的模式。
■用人工智能量化眼底镶嵌可以帮助发现早期近视性黄斑病变。
