PDF(Pubmed)
Abstract：
The goal-setting process is pivotal in managing patients with disabling spasticity. This case-control study assessed the role of diagnostic nerve blocks in guiding the goal-setting process within goal-targeted treatment of spasticity with botulinum neurotoxin-A. In this case-control study, patients with disabling spasticity underwent either a goal-setting process based on the patient\'s needs and clinical evaluation (control group) or additional diagnostic nerve block procedures (case group). All enrolled patients underwent a focal treatment with botulinum neurotoxin-A injection and a 1-month follow-up evaluation during which goal achievement was quantified using the goal attainment scaling-light score system. Data showed a higher goal achievement rate in the case group (70%) than in the control group (40%). In conclusion, diagnostic nerve blocks may help guide the goal-setting process within goal-targeted treatment of spasticity with botulinum neurotoxin-A towards more realistic and achievable goals, thereby improving the outcomes of botulinum neurotoxin-A injection. Future studies should better explore the role of diagnostic nerve blocks to further personalize botulinum neurotoxin-A according to individual patients\' preferences and requirements.
摘要：
目标设定过程对于治疗失能痉挛患者至关重要。这项病例对照研究评估了诊断性神经阻滞在用肉毒杆菌神经毒素A靶向治疗痉挛中指导目标设定过程的作用。在这项病例对照研究中，有致残性痉挛的患者根据患者的需要和临床评估(对照组)或额外的诊断性神经阻滞手术(病例组)进行目标设定.所有入选的患者都接受了肉毒杆菌神经毒素A注射的局灶性治疗，并进行了1个月的随访评估，在此期间，使用目标达成比例-轻度评分系统对目标达成进行了量化。数据显示，病例组（70％）的目标实现率高于对照组（40％）。总之,诊断性神经阻滞可能有助于指导目标设定过程中的目标靶向治疗痉挛与肉毒杆菌神经毒素-A朝向更现实和可实现的目标，从而改善肉毒杆菌神经毒素A注射的结果。未来的研究应更好地探索诊断性神经阻滞的作用，以根据患者的喜好和要求进一步个性化肉毒杆菌神经毒素A。
