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Abstract：
The allogeneic follicular fosterage (AFF) technique transfers cumulus-oocyte complexes (COCs) from pubertal female animals to the dominant follicles of adult female animals for further development, allowing the COCs to further develop in a completely in vivo environment. This article reviews the history of AFF and JIVET and their effects on oocyte and embryo development as well as freezing resistance. Improving the efficiency and reproducibility of AFF technology is crucial to its clinical application. This article discusses factors that affect the success rate of AFF, including differences in specific technical procedures and differences between pubertal and adult follicles. Designing standardized procedures and details to improve the synchronization of donor COCs and recipient follicle maturity and reducing the damage to COCs caused by follicular aspiration may be the direction for improving the success rate of AFF in the future.
摘要：
同种异体卵泡寄养（AFF）技术将青春期雌性动物的卵丘-卵母细胞复合物（COCs）转移到成年雌性动物的优势卵泡中进行进一步发育，允许COCs在完全体内环境中进一步发展。本文综述了AFF和JIVET的发展历史及其对卵母细胞和胚胎发育以及抗冻性的影响。提高AFF技术的效率和可重复性对其临床应用至关重要。本文讨论了影响AFF成功率的因素,包括特定技术程序的差异以及青春期和成年卵泡之间的差异。设计标准化程序和细节，以提高供体COC和受体卵泡成熟度的同步性，减少卵泡抽吸对COC的损害，可能是未来提高AFF成功率的方向。
