关键词: Staphylococcus aureus animal model infection rat

来  源:   DOI:10.3390/pathogens13060434   PDF(Pubmed)

Abstract:
Staphylococcus aureus (S. aureus) is a major human pathogen and can cause a wide range of diseases, including pneumonia, osteomyelitis, skin and soft tissue infections (SSTIs), endocarditis, mastitis, bacteremia, and so forth. Rats have been widely used in the field of infectious diseases due to their unique advantages, and the models of S. aureus infections have played a pivotal role in elucidating their pathogenic mechanisms and the effectiveness of therapeutic agents. This review outlined the current application of rat models in S. aureus infections and future prospects for rat models in infectious diseases caused by S. aureus.
摘要:
金黄色葡萄球菌(S。金黄色葡萄球菌)是一种主要的人类病原体,可以引起广泛的疾病,包括肺炎,骨髓炎,皮肤和软组织感染(STTI),心内膜炎,乳腺炎,菌血症,等等。大鼠因其独特的优势在感染性疾病领域得到了广泛的应用,金黄色葡萄球菌感染模型在阐明其致病机制和治疗剂的有效性方面发挥了关键作用。本文综述了大鼠模型在金黄色葡萄球菌感染中的应用现状,并对大鼠模型在金黄色葡萄球菌引起的感染性疾病中的应用前景进行了展望。
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