PDF(Pubmed)
Abstract：
The design of new, biomimetic biomaterials is of great strategic interest and is converging for many applications, including in implantology. This study explores a novel approach to improving dental implants. Although endosseous TA6V alloy dental implants are widely used in oral implantology, this material presents significant challenges, notably the prevalence of peri-implantitis. Therefore, in this study, we investigate a new advance in the design of hybrid medical devices. This involves the design of a Ca-SZ coating deposited by PVD on a TA6V substrate. This approach aims to overcome the inherent limitations of each of these materials, namely TA6V\'s susceptibility to peri-implantitis on the one hand and zirconia\'s excessively high Young\'s modulus compared with bone on the other, while benefiting from their respective advantages, such as the ductility of TA6V and the excellent biocompatibility of zirconia, offering relevant prospects for the design of high-performance implantable medical devices. This study integrates characterisation techniques, focusing on the structural and elemental analysis of the Ca-SZ coating by XRD and TEM. The results suggest that this coating combines a tetragonal structure, a uniform morphology with no apparent defects, a clean interface highlighting good adhesion, and a homogeneous composition of calcium, predisposing it to optimal biocompatibility. All of these findings make this innovative coating a particularly suitable candidate for application in dental implantology.
摘要：
新的设计，仿生生物材料具有极大的战略意义，并且正在融合许多应用，包括种植学。本研究探索了一种改善牙种植体的新方法。虽然骨内TA6V合金牙种植体广泛应用于口腔种植学，这种材料提出了重大挑战，尤其是种植体周围炎的患病率。因此,在这项研究中，我们研究了混合医疗设备设计的新进展。这涉及通过PVD在TA6V衬底上沉积的Ca-SZ涂层的设计。这种方法旨在克服每种材料的固有局限性，即一方面TA6V对种植体周围炎的敏感性，另一方面氧化锆与骨骼相比具有过高的杨氏模量，在受益于各自优势的同时，如TA6V的延展性和氧化锆优异的生物相容性，为高性能植入式医疗器械的设计提供相关前景。这项研究整合了表征技术，通过XRD和TEM对Ca-SZ涂层进行了结构和元素分析。结果表明，该涂层结合了四方结构，均匀的形态，没有明显的缺陷，一个干净的界面突出良好的附着力，和钙的均匀成分，使其成为最佳的生物相容性。所有这些发现使这种创新的涂层特别适合应用于牙科种植学。
