PDF(Pubmed)
Abstract：
The incidence and distribution of coccidioidomycosis are increasing. Information scarcity is evident in Mexico, particularly in non-endemic zones and specific populations. We compared the treatment and outcomes for patients with isolated pulmonary infections and those with disseminated coccidioidomycosis, including mortality rates within six weeks of diagnosis. Of 31 CM cases, 71% were male and 55% were disseminated. For 42% of patients, there was no evidence of having lived in or visited an endemic region. All patients had at least one comorbidity, and 58% had pharmacologic immunosuppressants. The general mortality rate was 30%; without differences between disseminated and localized disease. In our research, we describe a CM with a high frequency of disseminated disease without specific risk factors and non-significant mortality. Exposure to endemic regions was not found in a considerable number of subjects. We consider diverse reasons for why this may be, such as climate change or migration.
摘要：
球孢子菌病的发病率和分布正在增加。信息稀缺在墨西哥很明显，特别是在非地方病区和特定人群中。我们比较了孤立性肺部感染患者和播散性球孢子菌病患者的治疗和结果，包括诊断后六周内的死亡率。在31厘米的病例中，71%为男性，55%为播散。对于42%的患者来说，没有证据表明曾居住或访问过流行地区。所有患者都有至少一种合并症，58%有药物免疫抑制剂。一般死亡率为30％；传播和局部疾病之间没有差异。在我们的研究中,我们描述了一个传播性疾病频率高的CM,没有特定的危险因素,也没有显著的死亡率.在相当多的受试者中未发现暴露于流行区域。我们考虑不同的原因，例如气候变化或移民。
