PDF(Pubmed)
Abstract：
The inappropriate use of antibiotics gives rise to detrimental consequences, both physical and emotional, with a decreased quality of life and higher levels of anxiety and depression. The current observational study aimed to investigate the association between awareness, beliefs, and behaviors toward antibiotics, highlighting the modulating role of individual and psychological factors in response to illness and medication. Through an online questionnaire, several psychological indexes, as well as knowledge of, attitude toward, and experiences with antibiotics, both individual and family-related, were assessed in a sample of 100 responders (74 females, mean age 33.37 ± 11.36). A positive association between intake behavior, awareness, and individual attitude emerged. Familial approach to antibiotics appears as a predictor of individual attitude and behavior toward these drugs, and awareness about antibiotic risks mediate the relationship between the tendency to be more compliant with prescriptions (R2 = 0.300; MSE = 1.541; F(2, 98) = 20.737; p < 0.0001). Moreover, individuals with a personality characterized by higher conscientiousness are more aware of antibiotic risks (p < 0.01), whereas individuals with a lower awareness are those with higher indexes of psychophysical discomfort (i.e., anxiety, perceived stress, somatization) and levels of emotional rebound (p < 0.05). Anxiety (F(3, 96) = 3.874; p = 0.012; R2 = 0.108) and somatization (F(2, 97) = 3.114; p = 0.030; R2 = 0.089) also significatively moderated the intake behavior, despite the family approach. Overall, the current study provides preliminary findings regarding the way in which family experiences and individual psychological aspects may be influencing factors in the behavior and attitude towards antibiotics and can be used to plan patient-centered therapeutic communication and education.
摘要：
抗生素的不当使用会产生有害的后果，身体和情感，生活质量下降，焦虑和抑郁水平升高。当前的观察性研究旨在调查意识之间的关联，信仰,以及对抗生素的行为，强调个体和心理因素在疾病和药物反应中的调节作用。通过在线问卷，几个心理指标，以及知识，态度,和抗生素的经验，与个人和家庭有关，在100名响应者的样本中进行了评估(74名女性，平均年龄33.37±11.36）。摄入行为之间的正相关，意识,个人的态度出现了。抗生素的家族性方法似乎是个体对这些药物的态度和行为的预测因子，和对抗生素风险的认识介导了更多的处方依从性倾向之间的关系（R2=0.300;MSE=1.541;F（2，98）=20.737;p<0.0001）。此外，具有较高自觉性的人格的个体对抗生素风险的意识更强(p<0.01)，而意识较低的人是心理生理不适指数较高的人(即，焦虑,感知压力，躯体化)和情绪反弹水平(p<0.05)。焦虑(F(3,96)=3.874;p=0.012;R2=0.108)和躯体化(F(2,97)=3.114;p=0.030;R2=0.089)也显著调节了摄入行为，尽管家庭的方式。总的来说,本研究提供了有关家庭经历和个体心理方面可能影响抗生素行为和态度的方式的初步发现,并可用于计划以患者为中心的治疗性沟通和教育.
