在 TP53 突变的小细胞膀胱癌中对 Lurbintedin 的持久客观反应 : 一种分子导向策略。
关键词: lurbinectedin neuroendocrine carcinoma of the bladder next-generation sequencing small cell bladder cancer targeted therapy transcription factors urothelial carcinoma
Mesh : Humans Carbolines / therapeutic use Urinary Bladder Neoplasms / drug therapy genetics pathology Heterocyclic Compounds, 4 or More Rings / therapeutic use pharmacology Mutation Tumor Suppressor Protein p53 / genetics Male Carcinoma, Small Cell / drug therapy genetics Heterocyclic Compounds, 3-Ring / therapeutic use Antineoplastic Agents / therapeutic use Middle Aged
来 源:
DOI:10.3390/curroncol31060254
PDF(Pubmed)