PDF(Pubmed)
Abstract：
(1) Background: Breast cancer is the leading malignancy worldwide, and in Ghana, it has a poor overall survival rate. However, approximately 50% of cases are cases of early-stage disease, and with advances in breast cancer treatment and improvements in survival, quality of life (QOL) is becoming as important as the treatment of the disease. (2) Methodology: This was a cross-sectional study of survivors who had breast-conserving surgery (BCS), mastectomy only (M) and mastectomy with breast reconstruction (BRS) from 2016 to 2020 at a tertiary hospital in Ghana, comparatively assessing their QOL using EORTC QLQ C-30 and EORTC QLQ BR-23. (3) Results: The study participants had an overall global health status (GHS) median score of 83.3 [IQR: 66.7-91.7] with no significant differences between the surgery types. The BRS group had statistically significant lower median scores for the functional scale (82.8 and 51.0) and the highest scores for the symptomatic scale (15.7 and 16.5). Body image was significantly lowest for the BRS group (83.3) [68.8-91.7] and highest (100) [91.7-100] for the BCS group (p < 0.001). (4) Conclusion: There is a need to develop support systems tailored at improving the QOL of breast cancer survivors taking into consideration the type of surgery performed.
摘要：
(1)研究背景:乳腺癌是全球范围内的主要恶性肿瘤,在加纳,总体生存率很低。然而,大约50%的病例是早期疾病，随着乳腺癌治疗的进步和生存率的提高，生活质量（QOL）正变得与疾病的治疗一样重要。（2）方法：这是一项对接受保乳手术（BCS）的幸存者的横断面研究，2016年至2020年在加纳的一家三级医院进行的仅乳房切除术（M）和乳房再造乳房切除术（BRS），使用EORTCQLQC-30和EORTCQLQBR-23比较评估他们的生活质量。（3）结果：研究参与者的总体健康状况（GHS）中位数为83.3[IQR：66.7-91.7]，手术类型之间没有显着差异。BRS组的功能量表中位数得分较低（82.8和51.0），症状量表得分最高（15.7和16.5）。BRS组的身体图像显着最低（83.3）[68.8-91.7]，而BCS组的身体图像最高（100）[91.7-100]（p<0.001）。（4）结论：有必要开发专门的支持系统，以改善乳腺癌幸存者的QOL，同时考虑所进行的手术类型。
