PDF(Pubmed)
Abstract：
Previous research has revealed that daily variations in human neurobehavioral functions are driven in part by the endogenous circadian system. The objective of this study was to explore whether there exists a circadian influence on performance regarding a risky decision-making task and to determine whether the performance changes with sleep deprivation (SD). Thirteen participants underwent a 39 h constant routine (CR) protocol, during which they remained awake in constant conditions and performed the BART (balloon analogue risk task) every two hours. The mean pumps (gains) (p < 0.001) and balloons popped (losses) (p = 0.003) exhibited variation during the CR. The reaction time (RT) also showed significant variation across the CR (p < 0.001), with slower mean RTs in the morning hours following SD. A greater risk propensity was observed around midday before SD and a lower risk propensity after 29.5 h of being awake. The sensitivity to punishment varied during the CR, but did not follow a predictable trend. Further research using real monetary incentives and neurophysiological measures is warranted to elucidate these findings.
摘要：
先前的研究表明，人类神经行为功能的日常变化部分是由内源性昼夜节律系统驱动的。这项研究的目的是探讨在危险的决策任务中是否存在昼夜节律对绩效的影响，并确定绩效是否随睡眠剥夺（SD）而变化。13名参与者接受了39小时恒定常规(CR)方案，在此期间，他们在恒定的条件下保持清醒，每两小时执行一次BART（气球模拟风险任务）。平均泵（增益）（p<0.001）和球囊爆裂（损失）（p=0.003）在CR期间表现出变化。反应时间（RT）也显示出整个CR的显着变化（p<0.001），SD后早晨的平均RTs较慢。在SD前中午左右观察到更高的风险倾向，而在清醒29.5小时后观察到更低的风险倾向。在CR期间，对惩罚的敏感性各不相同，但没有遵循可预测的趋势。使用实际货币激励和神经生理学措施进行进一步研究是必要的，以阐明这些发现。
