PDF(Pubmed)
Abstract：
UNASSIGNED: Chlamydia abortus pneumonia is very rare in normal people. At present, there is a lack of clinical data on the clinical characteristics and diagnosis and treatment experience of patients with this type of infection. Our team had recently treated 7 cases of these patients. This study aims to comprehensively summarize and analyze the clinical characteristics and treatment methods of Chlamydia abortus pneumonia, and to provide clinical evidence for the diagnosis and treatment of Chlamydia abortus pneumonia.
UNASSIGNED: Clinical data were retrospectively collected from patients diagnosed with Chlamydia abortus pneumonia through metagenomic next-generation sequencing (mNGS) at the Department of Pulmonary and Critical Care Medicine, Meizhou People\'s Hospital.
UNASSIGNED: Seven patients with Chlamydia abortus pneumonia reported a history of poultry exposure, experiencing fever alongside respiratory or digestive symptoms. Marked elevation of blood inflammation markers, accompanied by hypoproteinemia and liver damage, was observed. Chest CT scans revealed pneumonia and pleural effusion. Chlamydia abortus was detected in blood or bronchoalveolar lavage fluid (BALF) through mNGS, often co-occurring with Chlamydia psittaci or other bacteria infections. Notably, Doxycycline demonstrated efficacy in treating Chlamydia abortus.
UNASSIGNED: Chlamydia abortus infection is a zoonotic disease, particularly among individuals with a history of poultry exposure, and mNGS emerges as a reliable diagnostic tool for its detection. Chlamydia abortus infection manifests with systemic and lung inflammation, effectively addressed through Doxycycline therapy.
UNASSIGNED: Clinical data were retrospectively collected from patients diagnosed with Chlamydia abortus pneumonia through metagenomic next-generation sequencing (mNGS) at the Department of Pulmonary and Critical Care Medicine, Meizhou People\'s Hospital.
UNASSIGNED: Seven patients with Chlamydia abortus pneumonia reported a history of poultry exposure, experiencing fever alongside respiratory or digestive symptoms. Marked elevation of blood inflammation markers, accompanied by hypoproteinemia and liver damage, was observed. Chest CT scans revealed pneumonia and pleural effusion. Chlamydia abortus was detected in blood or bronchoalveolar lavage fluid (BALF) through mNGS, often co-occurring with Chlamydia psittaci or other bacteria infections. Notably, Doxycycline demonstrated efficacy in treating Chlamydia abortus.
UNASSIGNED: Chlamydia abortus infection is a zoonotic disease, particularly among individuals with a history of poultry exposure, and mNGS emerges as a reliable diagnostic tool for its detection. Chlamydia abortus infection manifests with systemic and lung inflammation, effectively addressed through Doxycycline therapy.
摘要：
■流产衣原体肺炎在正常人中非常罕见。目前,缺乏有关此类感染患者的临床特征和诊治经验的临床数据。我们的团队最近治疗了这些患者中的7例。本研究旨在全面总结和分析流产衣原体肺炎的临床特点和治疗方法,为流产衣原体肺炎的诊断和治疗提供临床依据。
■通过肺和重症医学科的宏基因组下一代测序（mNGS）从诊断为流产衣原体肺炎的患者中回顾性收集临床数据，梅州市人民医院.
■7例流产衣原体肺炎患者报告有家禽接触史,伴有呼吸道或消化道症状的发热。血液炎症标志物明显升高，伴有低蛋白血症和肝损伤，被观察到。胸部CT扫描显示肺炎和胸腔积液。通过mNGS在血液或支气管肺泡灌洗液（BALF）中检测到流产衣原体，常与鹦鹉衣原体或其他细菌感染并存。值得注意的是,多西环素在治疗流产衣原体方面显示出疗效。
■流产衣原体感染是一种人畜共患疾病，特别是在有家禽接触史的个体中，mNGS成为其检测的可靠诊断工具。流产衣原体感染表现为全身和肺部炎症，通过多西环素治疗有效解决。
■通过肺和重症医学科的宏基因组下一代测序（mNGS）从诊断为流产衣原体肺炎的患者中回顾性收集临床数据，梅州市人民医院.
■7例流产衣原体肺炎患者报告有家禽接触史,伴有呼吸道或消化道症状的发热。血液炎症标志物明显升高，伴有低蛋白血症和肝损伤，被观察到。胸部CT扫描显示肺炎和胸腔积液。通过mNGS在血液或支气管肺泡灌洗液（BALF）中检测到流产衣原体，常与鹦鹉衣原体或其他细菌感染并存。值得注意的是,多西环素在治疗流产衣原体方面显示出疗效。
■流产衣原体感染是一种人畜共患疾病，特别是在有家禽接触史的个体中，mNGS成为其检测的可靠诊断工具。流产衣原体感染表现为全身和肺部炎症，通过多西环素治疗有效解决。
