关键词: Bipolar disorder India clinical research etiopathogenesis neurobiology

来  源:   DOI:10.4103/indianjpsychiatry.indianjpsychiatry_698_23   PDF(Pubmed)

Abstract:
UNASSIGNED: Bipolar disorder is one of the severe mental disorders that are associated with significant morbidity of the patients. Despite advancements in our understanding about the disorder, it remains a challenging proposition to treat bipolar disorder, largely since the prophylactic treatment of the disorder requires assessment of complex clinical algorithms. The revisions of the classificatory systems have also changed the conceptualization of the disorder. In this background, we conducted a review of the Indian studies conducted on the clinical aspects of bipolar disorder.
UNASSIGNED: A narrative review was conducted with focus on the literature published from India. The databases searched included PubMed, Scopus, and Google Scholar, and articles published over the last 15 years by Indian authors were included for this review.
UNASSIGNED: In our review, we could access a substantial volume of research published from India. We could identify studies that catered to most of the relevant themes in bipolar disorder including epidemiology, etiology, comorbidities, stigma, disability, clinical course, cognitive profile, pathways to care, and recovery.
UNASSIGNED: The research trajectory was in line with the research conducted elsewhere in the world. However, certain dissimilarities in terms of focus could also be observed. The possible reason behind this deviation could be the difference in clinical need and unique challenges faced in the management and rehabilitation of patients in bipolar disorder in Indian scenario.
摘要:
双相情感障碍是与患者的显著发病率相关的严重精神障碍之一。尽管我们对这种疾病的理解有了进步,治疗双相情感障碍仍然是一个具有挑战性的命题,主要是因为疾病的预防性治疗需要复杂的临床算法的评估。分类系统的修订也改变了该障碍的概念化。在这样的背景下,我们回顾了印度对双相情感障碍临床方面的研究.
进行了叙述性审查,重点是印度出版的文献。搜索的数据库包括PubMed,Scopus,和谷歌学者,本综述纳入了印度作者在过去15年中发表的文章。
在我们的评论中,我们可以从印度获得大量的研究成果。我们可以确定符合大多数双相情感障碍相关主题的研究,包括流行病学,病因学,合并症,污名,残疾,临床课程,认知概况,护理的途径,和恢复。
研究轨迹与世界其他地方进行的研究一致。然而,在焦点方面也可以观察到某些差异。这种偏差背后的可能原因可能是临床需求的差异以及在印度情况下双相情感障碍患者的管理和康复中面临的独特挑战。
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