PDF(Pubmed)
Abstract：
To review the latest surgical advances and evolving clinical use of scleral bio-tissue for reinforcement in the eye and review the published literature on novel surgical applications of scleral allograft bio-tissue. Conventional surgical procedures for scleral reinforcement using homologous scleral allograft have been traditionally ab-externo interventions comprising of anterior or posterior reinforcement of the sclera for clinical indications such as trauma, scleromalacia, glaucoma drainage device coverage, scleral perforation, buckle repair as well as posterior reinforcement for pathologic myopia and staphyloma. There have been a few novel ab-interno uses of scleral bio-tissue for reinforcement in both retina and glaucoma. Over the last decade, there has been an increase in peer-reviewed publications on scleral reinforcement, reflecting more interest in its clinical applications. With favorable biological and biomechanical properties, scleral allograft may be an ideal substrate for an array of new applications and surgical uses.
摘要：
回顾巩膜生物组织在眼部加固中的最新外科进展和不断发展的临床应用，并回顾有关巩膜同种异体生物组织的新型外科应用的已发表文献。使用同源巩膜同种异体移植物进行巩膜加固的常规外科手术是传统的外干预措施，包括巩膜的前或后加固以用于临床适应症，例如创伤，巩膜软化症,青光眼引流装置覆盖范围，巩膜穿孔,带扣修复以及病理性近视和葡萄肿的后路加固。巩膜生物组织在视网膜和青光眼中都有一些新的ab-interno用途。在过去的十年里，关于巩膜加固的同行评审出版物有所增加，反映了对其临床应用的更多兴趣。具有良好的生物学和生物力学特性，巩膜同种异体移植可能是一系列新应用和手术用途的理想基质。
