关键词: Adherence Adolescent Child and adolescent psychiatry Compliance Psychotropic medication

来  源:   DOI:10.1016/j.pedn.2024.06.019

Abstract:
OBJECTIVE: Although treatment non-adherence is relatively high among adolescents, there is a need for standardized measurement tools that measure adherence to treatment in adolescents. This study aimed to develop a new measurement tool to assess the adherence to treatment of adolescents with mental disorders who use psychotropic medication.
METHODS: The data of this methodologically designed study were collected between 01.04.2022 and 01.07.2023 in the Department of Child and Adolescent Psychiatry of a university hospital in the Aegean Region of Turkey. The Medication Adherence Reporting Scale and Adolescent Medical Adherence Scale draft form were used for data collection. The scale items were formed from the themes, sub-themes, and statements in the qualitative study that the researchers had conducted with adolescents with mental disorders and their parents, clinicians\' experiences, and systematic reviews and meta-synthesis in the literature. The study sample consisted of 95 adolescents with mental disorders. Exploratory factor analysis was performed with Varimax rotation to determine the factorial construct validity of the scale. Internal consistency analyses were performed in reliability analyses, and Cronbach\'s alpha coefficient was used.
RESULTS: The mean age of the adolescents was 14.18 years (1.81); 50.5% were male, and 96.8% were attending school. When the mental disorder diagnoses were analyzed, 65.3% of the adolescents were being followed up with Attention Deficit and Hyperactivity Disorder diagnoses, and 58.8% were using stimulants. The 12-item form of the Adolescent Medical Adherence Scale was found to have a three-factor structure with item-total correlation values ranging between 0.26 and 0.66, and these factors were named functionality, responsibility in treatment, and medication adherence. Factor loadings ranged between 0.44 and 0.86, and the items explained 62.98% of the total variance. The internal consistency coefficients of the scale were between 0.69 and 0.83 for the subscales and 0.82 for the total scale.
CONCLUSIONS: Based on the analysis and results used in this study, the Adolescent Medical Adherence Scale is a valid and reliable new measurement tool.
CONCLUSIONS: This tool can be used in clinical settings to evaluate adolescents\' treatment adherence and prognosis. Clinical studies conducted with adolescents can also determine adherence to treatment and affecting factors.
摘要:
目标:尽管青少年的治疗依从性相对较高,需要标准化的测量工具来测量青少年对治疗的依从性.这项研究旨在开发一种新的测量工具,以评估使用精神药物治疗的青少年精神障碍的依从性。
方法:这项方法学设计的研究的数据是在01.04.2022至01.07.2023之间在土耳其爱琴海地区一家大学医院的儿童和青少年精神病学系收集的。药物依从性报告量表和青少年医学依从性量表草稿表格用于数据收集。量表项目是由主题组成的,次主题,以及研究人员对患有精神障碍的青少年及其父母进行的定性研究中的陈述,临床医生的经验,文献中的系统综述和荟萃综合。研究样本包括95名患有精神障碍的青少年。使用Varimax旋转进行探索性因子分析,以确定量表的因子结构效度。在可靠性分析中进行了内部一致性分析,并使用了Cronbach的α系数。
结果:青少年的平均年龄为14.18岁(1.81岁);50.5%为男性,96.8%的人上学。当分析精神障碍诊断时,65.3%的青少年正在接受注意力缺陷和多动障碍的诊断。58.8%的人使用兴奋剂。青少年医学依从性量表的12项形式被发现具有三因素结构,项目总相关值在0.26和0.66之间,这些因素被命名为功能性,责任在治疗,和药物依从性。因子负荷在0.44和0.86之间,这些项目解释了总方差的62.98%。量表的内部一致性系数在子量表的0.69和0.83之间,在总量表的0.82之间。
结论:根据本研究中使用的分析和结果,青少年医学依从性量表是一种有效和可靠的新测量工具。
结论:该工具可用于临床评估青少年的治疗依从性和预后。对青少年进行的临床研究也可以确定对治疗的依从性和影响因素。
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