关键词: Blastomyces gilchristii Canada MycoSNP Ontario blastomycosis dimorphic fungi fungi genomic epidemiology outbreak respiratory infections

Mesh : Disease Outbreaks Blastomycosis / epidemiology microbiology Ontario / epidemiology Humans Phylogeny Blastomyces / genetics Genomics / methods Molecular Epidemiology Male Genome, Fungal Female Middle Aged

来  源:   DOI:10.3201/eid3007.231594   PDF(Pubmed)

Abstract:
Using phylogenomic analysis, we provide genomic epidemiology analysis of a large blastomycosis outbreak in Ontario, Canada, caused by Blastomyces gilchristii. The outbreak occurred in a locale where blastomycosis is rarely diagnosed, signaling a possible shift in geographically associated incidence patterns. Results elucidated fungal population genetic structure, enhancing understanding of the outbreak.
摘要:
使用系统基因组分析,我们提供了安大略省大型芽生菌病爆发的基因组流行病学分析,加拿大,由gilchristii胚芽引起的.爆发发生在很少诊断出芽生菌病的地方,预示着地理相关的发病模式可能发生转变。结果阐明了真菌种群的遗传结构,加强对疫情的了解。
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