关键词: carcinoma elevated serum tumor markers orchidectomy testicular germ cell tumors tmgct

来  源:   DOI:10.7759/cureus.61062   PDF(Pubmed)

Abstract:
We report the case of a 23-year-old male presenting with right testicular swelling, post-coital pain, and fever. Initial MRI and local examination suggested testicular carcinoma. Elevated serum alpha-fetoprotein (AFP) and lactate dehydrogenase (LDH) levels were observed. Biopsy confirmed a mixed germ cell tumor (MGCT). Concurrently, the patient was diagnosed with an infection and treated with antibiotics. Remarkably, following antibiotic therapy, fever resolved, and tumor marker levels significantly decreased. Subsequent orchidectomy confirmed the diagnosis of MGCT. This case underscores the importance of recognizing and treating concurrent infections, which may influence both clinical presentation and tumor marker levels in testicular germ cell tumors.
摘要:
我们报道了一个23岁男性出现右睾丸肿胀的病例,性交后疼痛,和发烧。初诊MRI及局部检查提示睾丸癌。观察到血清甲胎蛋白(AFP)和乳酸脱氢酶(LDH)水平升高。活检证实为混合性生殖细胞肿瘤(MGCT)。同时,患者被诊断为感染,并接受抗生素治疗。值得注意的是,抗生素治疗后,发烧解决了,肿瘤标志物水平显著下降。随后的睾丸切除术证实了MGCT的诊断。该病例强调了识别和治疗并发感染的重要性,这可能会影响睾丸生殖细胞肿瘤的临床表现和肿瘤标志物水平。
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