关键词: acupuncture aspiration dysphagia meta-analysis stroke systematic review

来  源:   DOI:10.3389/fneur.2024.1305056   PDF(Pubmed)

Abstract:
UNASSIGNED: This systematic review and meta-analysis aims to systematically evaluate the effectiveness and safety of acupuncture in the treatment of aspiration caused by post-stroke dysphagia.
UNASSIGNED: A computer search was conducted in nine databases, including the China National Knowledge Infrastructure (CNKI), China Science and Technology Journal (VIP), Wan-fang Database, China Biomedical Literature Database (CBM), PubMed, Web of Science, Cochrane Library, Embase, and Chinese Clinical Trial Registry (ChiCTR), from their inception until April 2024. Clinical randomized controlled trials comparing acupuncture combined therapy or single therapy with control interventions for the treatment of aspiration caused by post-stroke dysphagia were included. The primary outcome measure was the Penetration Aspiration Scale (PAS), and secondary outcome measures included the overall effective rate, video fluoroscopic swallowing study (VFSS), and hyoid bone displacement. The statistical analysis was performed using RevMan 5.3 and Stata 16.0.
UNASSIGNED: A total of 16 articles involving 1,284 patients were included. The meta-analysis results showed that acupuncture combined therapy or single therapy was more effective in improving PAS scores compared to conventional rehabilitation therapy or balloon dilation of the catheter [WMD = -1.05, 95% CI (-1.30, -0.80), Z = 0.82, p = 0.00 < 0.05]. It was also more effective in improving VFSS scores [WMD = 1.32, 95% CI (0.08, 2.55), Z = 2.09, p = 0.04 < 0.05] and hyoid bone displacement [WMD = 2.02, 95% CI (0.86, 3.18), Z = 3.41, p = 0.00 < 0.05]. Additionally, acupuncture had a higher overall effective rate [WMD = 1.21, 95% CI (1.14, 1.29), Z = 5.76, p = 0.00 < 0.05] and a lower incidence of adverse events. Sensitivity analysis indicated that the literature had minimal impact on the results, and bias tests showed no publication bias.
UNASSIGNED: Acupuncture combined therapy and acupuncture single therapy can effectively improve aspiration caused by post-stroke dysphagia with a low incidence of adverse events. However, due to the low quality of the included literature, more high-quality randomized controlled trials are still needed to confirm the effectiveness and safety of acupuncture in the treatment of aspiration caused by post-stroke dysphagia.
UNASSIGNED: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462707, identifier CRD42023462707.
摘要:
这项系统综述和荟萃分析旨在系统评估针灸治疗中风后吞咽困难引起的误吸的有效性和安全性。
在9个数据库中进行了计算机搜索,包括中国国家知识基础设施(CNKI),中国科学技术学报(VIP),万方数据库,中国生物医学文献数据库(CBM),PubMed,WebofScience,科克伦图书馆,Embase,和中国临床试验注册中心(ChiCTR),从成立到2024年4月。纳入临床随机对照试验,比较针灸联合治疗或单一治疗与对照干预治疗中风后吞咽困难引起的误吸。主要结果测量是渗透吸气量表(PAS),次要结果指标包括总有效率,视频透视吞咽研究(VFSS),和舌骨移位。使用RevMan5.3和Stata16.0进行统计分析。
共纳入16篇文章,涉及1,284例患者。荟萃分析结果显示,与常规康复治疗或球囊扩张导管相比,针刺联合治疗或单一治疗在改善PAS评分方面更有效[WMD=-1.05,95%CI(-1.30,-0.80),Z=0.82,p=0.00<0.05]。在改善VFSS评分方面也更有效[WMD=1.32,95%CI(0.08,2.55),Z=2.09,p=0.04<0.05,舌骨位移[WMD=2.02,95%CI(0.86,3.18),Z=3.41,p=0.00<0.05]。此外,针刺有较高的总有效率[WMD=1.21,95%CI(1.14,1.29),Z=5.76,p=0.00<0.05]和较低的不良事件发生率。敏感性分析表明,文献对结果的影响最小,和偏倚测试显示没有发表偏倚。
针刺联合疗法和针刺单一疗法可有效改善卒中后吞咽困难引起的误吸,不良事件发生率低。然而,由于收录文献的质量低,仍需要更多高质量的随机对照试验来证实针刺治疗卒中后吞咽困难所致误吸的有效性和安全性。
https://www.crd.约克。AC.uk/prospro/display_record.php?ID=CRD42023462707,标识符CRD42023462707。
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