PDF(Pubmed)
Abstract：
UNASSIGNED: Previous studies have yielded varying conclusions regarding the impact of single-patient room design on nosocomial infection in the intensive care unit (ICU). We aimed to examine the impact of ICU single-patient room design on infection control.
UNASSIGNED: We conducted a comprehensive search of PubMed, Embase, the Cochrane Library, Web of Science, CNKI, WanFang Data, and CBM databases from inception to October 2023, without language restrictions. We included observational cohort and quasi-experimental studies assessing the effect of single- versus multi-patient rooms on infection control in the ICU. Outcomes measured included the nosocomial infection rate, incidence density of nosocomial infection, nosocomial colonization and infection rate, acquisition rate of multidrug-resistant organisms (MDROs), and nosocomial bacteremia rate. The choice of effect model was determined by heterogeneity.
UNASSIGNED: Our final analysis incorporated 12 studies involving 12,719 patients. Compared with multi-patient rooms in the ICU, single-patient rooms demonstrated a significant benefit in reducing the nosocomial infection rate (odds ratio [OR]: 0.68; 95% confidence interval [CI]: 0.59, 0.79; p < 0.00001). Analysis based on nosocomial infection incidence density revealed a statistically significant reduction in single-patient rooms (OR: 0.64; 95% CI: 0.44, 0.92; p = 0.02). Single-patient rooms were associated with a marked decrease in nosocomial colonization and infection rate (OR: 0.44; 95% CI: 0.32, 0.62; p < 0.00001). Furthermore, patients in single-patient rooms experienced lower nosocomial bacteremia rate (OR: 0.73; 95% CI: 0.59, 0.89; p = 0.002) and lower acquisition rate of MDROs (OR: 0.41; 95% CI: 0.23, 0.73; p = 0.002) than those in multi-patient rooms.
UNASSIGNED: Implementation of single-patient rooms represents an effective strategy for reducing nosocomial infections in the ICU.
UNASSIGNED: https://www.crd.york.ac.uk/PROSPERO/).
UNASSIGNED: We conducted a comprehensive search of PubMed, Embase, the Cochrane Library, Web of Science, CNKI, WanFang Data, and CBM databases from inception to October 2023, without language restrictions. We included observational cohort and quasi-experimental studies assessing the effect of single- versus multi-patient rooms on infection control in the ICU. Outcomes measured included the nosocomial infection rate, incidence density of nosocomial infection, nosocomial colonization and infection rate, acquisition rate of multidrug-resistant organisms (MDROs), and nosocomial bacteremia rate. The choice of effect model was determined by heterogeneity.
UNASSIGNED: Our final analysis incorporated 12 studies involving 12,719 patients. Compared with multi-patient rooms in the ICU, single-patient rooms demonstrated a significant benefit in reducing the nosocomial infection rate (odds ratio [OR]: 0.68; 95% confidence interval [CI]: 0.59, 0.79; p < 0.00001). Analysis based on nosocomial infection incidence density revealed a statistically significant reduction in single-patient rooms (OR: 0.64; 95% CI: 0.44, 0.92; p = 0.02). Single-patient rooms were associated with a marked decrease in nosocomial colonization and infection rate (OR: 0.44; 95% CI: 0.32, 0.62; p < 0.00001). Furthermore, patients in single-patient rooms experienced lower nosocomial bacteremia rate (OR: 0.73; 95% CI: 0.59, 0.89; p = 0.002) and lower acquisition rate of MDROs (OR: 0.41; 95% CI: 0.23, 0.73; p = 0.002) than those in multi-patient rooms.
UNASSIGNED: Implementation of single-patient rooms represents an effective strategy for reducing nosocomial infections in the ICU.
UNASSIGNED: https://www.crd.york.ac.uk/PROSPERO/).
摘要：
■先前的研究得出了关于单患者房间设计对重症监护病房（ICU）医院感染影响的不同结论。我们旨在研究ICU单病房设计对感染控制的影响。
■我们对PubMed进行了全面搜索，Embase,Cochrane图书馆,WebofScience,CNKI,万方数据,和CBM数据库从开始到2023年10月，没有语言限制。我们纳入了观察性队列和准实验研究，评估了ICU中单室和多病房对感染控制的影响。测量的结果包括医院感染率，医院感染发生率密度，医院定植和感染率，多药耐药生物(MDROs)的获取率，和院内菌血症率。效应模型的选择取决于异质性。
■我们的最终分析纳入了12项研究，涉及12,719名患者。与ICU中的多病室相比，单病房在降低医院感染率方面有显著益处(比值比[OR]:0.68;95%置信区间[CI]:0.59,0.79;p<0.00001).基于医院感染发生率密度的分析显示，单患者房间的差异有统计学意义（OR：0.64；95％CI：0.44，0.92；p=0.02）。单病房与医院定植和感染率显著下降相关(OR:0.44;95%CI:0.32,0.62;p<0.00001)。此外，单病房患者的医院菌血症率(OR:0.73;95%CI:0.59,0.89;p=0.002)较低,MDRO的获取率(OR:0.41;95%CI:0.23,0.73;p=0.002)较多病房患者低.
■实施单病房是减少ICU医院感染的有效策略。
■https://www.crd.约克。AC.英国/PROSPERO/)。
■我们对PubMed进行了全面搜索，Embase,Cochrane图书馆,WebofScience,CNKI,万方数据,和CBM数据库从开始到2023年10月，没有语言限制。我们纳入了观察性队列和准实验研究，评估了ICU中单室和多病房对感染控制的影响。测量的结果包括医院感染率，医院感染发生率密度，医院定植和感染率，多药耐药生物(MDROs)的获取率，和院内菌血症率。效应模型的选择取决于异质性。
■我们的最终分析纳入了12项研究，涉及12,719名患者。与ICU中的多病室相比，单病房在降低医院感染率方面有显著益处(比值比[OR]:0.68;95%置信区间[CI]:0.59,0.79;p<0.00001).基于医院感染发生率密度的分析显示，单患者房间的差异有统计学意义（OR：0.64；95％CI：0.44，0.92；p=0.02）。单病房与医院定植和感染率显著下降相关(OR:0.44;95%CI:0.32,0.62;p<0.00001)。此外，单病房患者的医院菌血症率(OR:0.73;95%CI:0.59,0.89;p=0.002)较低,MDRO的获取率(OR:0.41;95%CI:0.23,0.73;p=0.002)较多病房患者低.
■实施单病房是减少ICU医院感染的有效策略。
■https://www.crd.约克。AC.英国/PROSPERO/)。
