关键词: FORLI cancer head and neck surgery history larynx otolaryngology total laryngectomy

来  源:   DOI:10.3389/fonc.2024.1351549   PDF(Pubmed)

Abstract:
The inaugural total laryngectomy in history was conducted by Billroth in 1873. Nevertheless, significant enhancements to the technique were achieved through the contributions of Gluck, Sorensen, and various other surgeons. Throughout the twentieth century, advancements in anesthesia, infectious disease, hospital hygiene, antibiotic therapy, resuscitation, and the expertise of numerous laryngologists elevated total laryngectomy to a pivotal surgical intervention in head and neck surgery. The latter half of the twentieth century witnessed a paradigm shift with the emergence of organ preservation protocols. Total laryngectomy became the preferred choice for patients experiencing radiotherapy failure. However, the widespread use of laryngeal conservative treatments appears to be correlated with a decline in overall survival rates in the United States and Europe. The evolution of new minimally invasive surgical approaches in the twenty-first century may usher in a revolutionary era in the management of laryngeal carcinoma, offering the potential for improved survival and functional outcomes.
摘要:
Billroth于1873年进行了历史上首次的全喉切除术。然而,通过Gluck的贡献,该技术实现了显著的增强,索伦森,和其他各种外科医生。在整个二十世纪,麻醉的进步,传染病,医院卫生,抗生素治疗,复苏,许多喉科医师的专业知识将全喉切除术提升为头颈部手术的关键手术干预。二十世纪下半叶随着器官保存协议的出现,见证了范式的转变。全喉切除术成为放疗失败患者的首选。然而,在美国和欧洲,喉部保守治疗的广泛使用似乎与总体生存率下降相关.21世纪新的微创手术方法的发展可能会迎来喉癌治疗的革命性时代,提供改善生存和功能结果的潜力。
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