Abstract：
BACKGROUND Post-donation regret in family living liver donors can impact their mental well-being. This study examined whether the relationship between post-donation regret and anxiety is mediated by family relationships and a sense of mastery. MATERIAL AND METHODS We conducted a secondary analysis of de-identified cross-sectional data from a prior study that included 124 living liver donors. These donors underwent partial hepatectomy between January 2011 and March 2021 at a tertiary hospital in Seoul, South Korea. The data included demographic and clinical characteristics, along with the results from administering the following measures: the Post-Donation Regret Scale, Family Relationships Index, Pearlin Mastery Scale, and the Generalized Anxiety Disorder-2 scale. RESULTS Among family living liver donors, 5.6% had anxiety after donation. The total effect of post-donation regret on anxiety was significant (B=0.41, p<0.05). However, the direct effect of regret on anxiety was not significant (B=-0.05, p=0.733). Post-donation regret had indirect effects on anxiety, solely through family relationships (B=0.329, 95% CI=0.130, 0.563) and sequentially through family relationships and mastery (B=0.088, 95% CI=0.008, 0.232), even after controlling for sex, age, postoperative complications, years since donation, and recipient\'s death. In addition, postoperative complication was a predictor of anxiety (B=0.64, p<0.05). CONCLUSIONS Providing family-centered and mastery-enhancing interventions may help alleviate the anxiety of family living liver donors.
摘要：
背景技术家庭生活的肝脏捐献者的捐赠后遗憾会影响他们的心理健康。这项研究检查了捐赠后后悔和焦虑之间的关系是否由家庭关系和掌握感介导。材料和方法我们对来自先前研究的包括124个活体肝脏供体的去识别的横截面数据进行了二次分析。这些捐献者在2011年1月至2021年3月期间在首尔的一家三级医院接受了部分肝切除术，韩国。数据包括人口统计学和临床特征，以及执行以下措施的结果：捐赠后后悔量表，家庭关系指数,Pearlin掌握量表,和广义焦虑症-2量表。结果在家庭生活的肝脏供体，5.6%的人在捐赠后有焦虑。捐赠后后悔对焦虑的总影响显著(B=0.41,p<0.05)。然而,后悔对焦虑的直接影响不显著(B=-0.05,p=0.733)。捐赠后的遗憾对焦虑有间接影响，仅通过家庭关系（B=0.329，95％CI=0.130，0.563）并依次通过家庭关系和掌握（B=0.088，95％CI=0.008，0.232），即使在控制性生活之后，年龄,术后并发症,捐赠多年来，和接受者的死亡。此外,术后并发症是焦虑的预测因子(B=0.64,p<0.05)。结论提供以家庭为中心和加强掌握的干预措施可能有助于减轻家庭生活肝脏供体的焦虑。
