关键词: Burkholderia cenocepacia Outbreak PFGE

Mesh : Humans Electrophoresis, Gel, Pulsed-Field Burkholderia Infections / epidemiology microbiology Tertiary Care Centers Disease Outbreaks Burkholderia cenocepacia / genetics classification isolation & purification Intensive Care Units Cross Infection / epidemiology microbiology India / epidemiology Male Female Middle Aged Adult Molecular Typing / methods

来  源:   DOI:10.1016/j.ijmmb.2024.100655

Abstract:
Nosocomial outbreaks of Burkholderia cepacia complex, transmitted through contaminated medical surfaces or equipment have been reported. Pulsed-field Gel Electrophoresis (PFGE) is recognized as the \"gold standard\" for molecular subtyping, yet studies on clonal relationships in India are limited. PFGE was used to study the clonal relationships of 22 isolates of Burkholderia cenocepacia from 12 patients admitted to a critical care unit during 2 months (November and December 2021). PFGE revealed three different profiles with 15 isolates belonging to a single cluster suggesting a common source within the hospital, emphasizing the need for preventive measures to control B. cenocepacia transmission.
摘要:
洋葱伯克霍尔德菌的医院暴发,据报道,通过受污染的医疗表面或设备传播。脉冲场凝胶电泳(PFGE)被认为是分子亚型的“黄金标准”,然而,关于印度克隆关系的研究是有限的。PFGE用于研究2个月(2021年11月和12月)期间收治的12名重症监护病房患者的22个伯克霍尔德氏菌分离株的克隆关系。PFGE揭示了三个不同的概况,其中15个分离株属于一个单一的集群,表明医院内是一个共同的来源,强调需要采取预防措施来控制头孢双歧杆菌的传播。
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