PDF(Pubmed)
Abstract：
Dengue fever (DF) and tuberculosis (TB) present significant global health challenges, often with overlapping clinical features, especially when complicated by conditions like dengue encephalopathy. We present a case study involving an 84-year-old male with a complex medical history, encompassing pulmonary tuberculosis reactivation, who subsequently developed dengue encephalitis. This underscores the complexity of managing such cases in the geriatric population. Dengue encephalitis, once considered non-neurotropic, is increasingly recognized, necessitating consideration as a potential differential diagnosis in patients with neurological symptoms, particularly in endemic regions. Our patient exhibited typical DF symptoms alongside manifestations of encephalopathy. Concurrently, secondary TB reactivation was observed, emphasizing the intricate interplay between these diseases. Additionally, lower respiratory tract infection (LRTI) further complicated the clinical picture. Timely recognition and comprehensive management are crucial, as demonstrated in our case, where prompt reporting and conservative measures led to a favorable outcome.
摘要：
登革热（DF）和结核病（TB）带来了重大的全球健康挑战，通常具有重叠的临床特征，尤其是当并发登革热脑病等疾病时。我们提供了一个案例研究，涉及一名84岁男性，有复杂的病史，包括肺结核再激活，后来患上了登革热脑炎。这突显了在老年人群中管理此类病例的复杂性。登革热脑炎,曾经被认为是非亲神经的，越来越多的人认识到,有神经症状的患者需要考虑作为潜在的鉴别诊断，特别是在流行地区。我们的患者表现出典型的DF症状以及脑病的表现。同时,观察到继发性TB再激活，强调这些疾病之间错综复杂的相互作用。此外,下呼吸道感染（LRTI）进一步复杂化的临床表现。及时识别,综合治理至关重要,正如我们的案例所证明的，及时报告和保守措施导致了有利的结果。
