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Abstract：
Background A widely accepted set of imaging criteria or classification has not yet been adopted to evaluate response to treatment by percutaneous sclerotherapy for aneurysmal bone cyst (ABC). In this article, we described and illustrated the Royal Orthopaedic Hospital (ROH) scoring system which is a new, reproducible, and objective tool to evaluate the radiological response. We also reported our institutional experience in the efficacy of computed tomography (CT)-guided sclerotherapy for treating such lesions. Patients and Methods A retrospective analysis was conducted for 19 patients who underwent CT-guided sclerotherapy with doxycycline and albumin to treat ABC. Follow-up magnetic resonance imaging, at a minimum of 12 months, was assessed according to the four ROH scoring system parameters: cystic component, fluid-fluid level, presence of consolidation, and cortical integrity. The cumulative score was used to grade response as either: excellent, good, equivocal, or poor. Results Out of 19 patients with a mean age of 17.8 years, 11 cases occurred in the long bones, 5 cases in the pelvis, and 1 in each of the C3 vertebral body, scapula, and talus. The mean parameter of response score for cystic component was 2, fluid-fluid level was 1.3, consolidation was 2, and cortical integrity was 2.1. Four cases showed excellent response, 12 cases showed good response, 2 cases showed equivocal response, and 1 case showed poor response. Interrater reliability was excellent (κ = 0.9). Conclusion The ROH scoring system provides the radiologist and surgeon with an objective method to score imaging parameters of response independently and achieve a grade based on the cumulative score.
摘要：
背景尚未采用一组广泛接受的成像标准或分类来评估经皮硬化疗法治疗动脉瘤样骨囊肿（ABC）的反应。在这篇文章中,我们描述并说明了皇家骨科医院（ROH）评分系统，这是一种新的，可重复,和客观工具来评估放射学反应。我们还报告了我们在计算机断层扫描（CT）引导的硬化疗法治疗此类病变的疗效方面的机构经验。患者与方法对19例CT引导下多西环素和白蛋白硬化治疗ABC的患者进行回顾性分析。后续磁共振成像，至少12个月，根据四个ROH评分系统参数进行评估：囊性成分，流体-流体液位,整合的存在，和皮质的完整性。累积分数用于将反应评分为：优秀，不错,模棱两可,或者穷。结果19例患者平均年龄17.8岁,11例发生在长骨，5例骨盆，在每个C3椎体中都有1个，肩胛骨,还有距骨.囊性成分的反应评分的平均参数为2，流体水平为1.3，巩固为2，皮质完整性为2.1。4例反应良好,12例反应良好，2例出现模棱两可的反应，1例反应不佳。评分者间可靠性优异(κ=0.9)。结论ROH评分系统为放射科医师和外科医生提供了一种客观的方法，可以独立地对响应的成像参数进行评分，并根据累积评分得出等级。
