PDF(Pubmed)
Abstract：
Syphilis is a complex, systemic infectious disease caused by Treponema pallidum subspecies pallidum. Secondary syphilitic lesions typically manifest within 3 months following initial exposure to T. pallidum. The predominant cutaneous manifestations of secondary syphilis are macula and papule. Certain individuals with syphilis may present with an atypical rash during the secondary stage owing to immunosuppression and other factors. Herein, we report a rare case of atypical recurrent secondary syphilis around the anus in a 65-year-old woman. Based on cerebrospinal fluid findings and skin biopsy results, the patient was ultimately diagnosed as neurosyphilis and recurrent secondary syphilis. Following intravenous antibiotic therapy, the patient\'s rash improved significantly. This case underscores the importance for physicians to remain vigilant regarding the possibility of syphilis when encountering cases exhibiting unusual clinical manifestations, as a definitive diagnosis necessitates a comprehensive evaluation.
摘要：
梅毒是一个复杂的,由梅毒螺旋体亚种引起的全身性传染病。继发性梅毒性病变通常在最初暴露于梅毒螺旋体后3个月内出现。继发性梅毒的主要皮肤表现是黄斑和丘疹。由于免疫抑制和其他因素，某些梅毒患者在第二阶段可能出现非典型皮疹。在这里，我们报告了一例罕见的肛门周围非典型复发性二期梅毒病例，该病例为65岁女性。根据脑脊液检查结果和皮肤活检结果，患者最终诊断为神经梅毒和复发性二期梅毒。静脉注射抗生素治疗后，患者的皮疹明显改善。该病例强调了医生在遇到表现出异常临床表现的病例时对梅毒的可能性保持警惕的重要性。作为一个明确的诊断需要一个全面的评估。
