关键词: a systematic review oncology transitional cell carcinoma urinary bladder diverticulum urology

来  源:   DOI:10.7759/cureus.62974   PDF(Pubmed)

Abstract:
Intradiverticular transitional cell carcinoma (TCC) of the bladder poses unique challenges due to its presentation within the bladder diverticula. This review synthesizes current knowledge on the diagnosis and management of this condition, emphasizing the need for early detection to optimize patient outcomes. The literature underscores the importance of tailored treatment strategies, ranging from radical surgeries to adjuvant chemotherapy, to combat the aggressive nature of intradiverticular TCC. Additionally, stringent post-treatment surveillance protocols are vital in addressing high recurrence rates. Future research directions include biomarker identification, comparative efficacy studies of treatment modalities, and the exploration of innovative therapeutic approaches such as immunotherapy. Longitudinal studies analyzing patient outcomes will provide valuable insights into survival rates and quality of life post-treatment, informing future clinical guidelines. This comprehensive review aims to enhance understanding and management strategies for intradiverticular TCC, paving the way for improved patient care and outcomes in this challenging form of bladder cancer.
摘要:
膀胱内移行细胞癌(TCC)由于其在膀胱憩室内的表现而面临独特的挑战。这篇综述综合了关于这种疾病的诊断和管理的最新知识,强调早期检测以优化患者预后的必要性。文献强调了量身定制的治疗策略的重要性,从根治性手术到辅助化疗,来对抗内部TCC的侵略性。此外,严格的治疗后监测方案对于解决高复发率至关重要.未来的研究方向包括生物标志物识别、治疗方式的比较疗效研究,以及对免疫疗法等创新治疗方法的探索。分析患者预后的纵向研究将为治疗后的生存率和生活质量提供有价值的见解。通知未来的临床指南。这项全面审查旨在加强对室内TCC的理解和管理策略,为改善这种具有挑战性的膀胱癌的患者护理和预后铺平了道路。
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