关键词: Anesthesia Articaine Bupivacaine Pain Ropivacaine

来  源:   DOI:10.1007/s12663-021-01548-7   PDF(Pubmed)

Abstract:
UNASSIGNED: The aim of this study was to compare the anesthetic efficacy of 4% articaine, 0.5% bupivacaine and 0.5% ropivacaine (with 1:200,000 adrenaline) during surgical removal of impacted mandibular third molars.
UNASSIGNED: The study included 75 patients randomly divided into three equal groups of 25 patients each. The study variables were: onset of anesthetic action, duration of surgery and anesthesia and postoperative analgesia. A visual analog scale was used to assess pain at different time intervals. Statistical analysis revealed insignificant difference among groups in terms of volume of anesthetic solution used, quality of anesthesia, surgical difficulty and duration of surgery.
UNASSIGNED: The mean onset time was significantly (P < 0.001) shorter for articaine (1.14 min) than ropivacaine (2.18 min) and bupivacaine (2.33 min). However, the duration of anesthesia as well as analgesia was significantly (P < 0.001) longer for bupivacaine (483.6 min and 464 min) and ropivacaine (426.6 min and 459 min) as compared to articaine (232.8 min and 191.4 min), respectively. Also, on comparing three groups pain scores at 6th postoperative hour were significant (P < 0.01).
UNASSIGNED: Ropivacaine and bupivacaine can be safely used in patients where longer duration of surgery is anticipated.
摘要:
这项研究的目的是比较4%阿替卡因的麻醉效果,0.5%布比卡因和0.5%罗哌卡因(1:200,000肾上腺素)在手术切除下颌第三磨牙时。
该研究包括75名患者,随机分为3组,每组25名患者。研究变量是:麻醉作用的开始,手术时间和麻醉和术后镇痛。使用视觉模拟量表来评估不同时间间隔的疼痛。统计分析显示,在使用的麻醉溶液的体积方面,组间差异无统计学意义。麻醉质量,手术难度和手术持续时间。
阿替卡因(1.14min)的平均起效时间明显短于(P<0.001)罗哌卡因(2.18min)和布比卡因(2.33min)。然而,与阿替卡因(232.8min和191.4min)相比,布比卡因(483.6min和464min)和罗哌卡因(426.6min和459min)的麻醉和镇痛持续时间明显(P<0.001)更长,分别。此外,三组术后6小时疼痛评分比较,差异有统计学意义(P<0.01)。
罗哌卡因和布比卡因可安全用于预期手术持续时间较长的患者。
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