UNASSIGNED: Twenty-four healthy cats were included in this study. The wavelength of LLLT was 830 nm with an output power of 200 mW through extraoral application, using fluences of 2 and 6 J/cm2 in continuous-wave mode. This study compared different distances (contact and non-contact) and three different transmission media (absent media, alcohol, and normal saline solution). Measurement of the laser power within the oral cavity is represented as the mean output power (MOP).
UNASSIGNED: Penetration efficacy was detectable for all fluences, distances, and transmission media, with an average buccal thickness of 2.68 mm. MOP did not differ between fluences of 2 and 6 J/cm2 (p = 0.19). In the absence of media, MOP was significantly higher compared with alcohol (p < 0.05) but was not significantly different from normal saline solution (p = 0.26).
UNASSIGNED: Extraoral application of LLLT demonstrated penetration efficacy through the buccal tissue with both contact and non-contact skin (<10 mm). This is a potential alternative treatment for oral diseases in clinical practice. However, there is a need for further study on the efficacy of treatment in clinical practice.
■本研究包括24只健康猫。通过口外应用,LLLT的波长为830nm,输出功率为200mW,在连续波模式下使用2和6J/cm2的通量。本研究比较了不同的距离(接触和非接触)和三种不同的传输介质(无介质,酒精,和生理盐水溶液)。口腔内激光功率的测量表示为平均输出功率(MOP)。
■所有注量的渗透功效均可检测到,距离,和传输介质,平均颊厚度为2.68毫米。MOP在2和6J/cm2的注量之间没有差异(p=0.19)。在没有媒体的情况下,与酒精相比,MOP显着较高(p<0.05),但与生理盐水溶液没有显着差异(p=0.26)。
■LLLT的口外应用证明了通过接触和非接触皮肤(<10mm)的颊组织的渗透功效。这是临床实践中口腔疾病的潜在替代疗法。然而,在临床实践中需要进一步研究治疗的疗效。