PDF(Pubmed)
Abstract：
UNASSIGNED: Determine if there is a difference in adverse events (AE) between right or left hepatic percutaneous biliary drain placement (PTBD) in patients with biliary strictures.
UNASSIGNED: This retrospective study included patients with benign or malignant biliary stricture treated with PTBD at a single institution from 7/28/2004-3/30/2021. 357 patients met inclusion criteria, 77 (21.6 %) had PTBD on the left and 280 (78.4 %) on the right. AEs associated with the initial drain placement or during subsequent intervention were collected and categorized. AEs that were grouped as periprocedural included: surgery, infection, hemorrhage, and drain failure. AEs in the postprocedural group included: chills, catheter displacement, cholangitis, biliary stones, drain malfunction, fever resolving without treatment, and pericatheter leakage. Surgery was considered a major AE and the remaining AEs were categorized as minor. Statistical analyses were performed using Logistic Regression Analysis and p-values less than 0.05 were considered statistically significant.
UNASSIGNED: Overall, there was no statistically significant difference in AEs between right and left drains in the periprocedural and postprocedural period (p = 0.832, OR = 0.95 and p = 0.808, OR = 0.93 respectively). When analyzing minor AEs individually, only cholangitis occurred at a higher rate on the right side (p = 0.033, OR = 0.43). There was no statistical difference in the rate of major AEs in the periprocedural period between left and right drains (p = 0.311, OR = 1.37).
UNASSIGNED: Current literature is equivocal when comparing right versus left percutaneous biliary drains. This analysis describes no statistically significant difference in AEs between right and left hepatobiliary drains aside from slightly higher incidence of cholangitis for right sided drains.
UNASSIGNED: This retrospective study included patients with benign or malignant biliary stricture treated with PTBD at a single institution from 7/28/2004-3/30/2021. 357 patients met inclusion criteria, 77 (21.6 %) had PTBD on the left and 280 (78.4 %) on the right. AEs associated with the initial drain placement or during subsequent intervention were collected and categorized. AEs that were grouped as periprocedural included: surgery, infection, hemorrhage, and drain failure. AEs in the postprocedural group included: chills, catheter displacement, cholangitis, biliary stones, drain malfunction, fever resolving without treatment, and pericatheter leakage. Surgery was considered a major AE and the remaining AEs were categorized as minor. Statistical analyses were performed using Logistic Regression Analysis and p-values less than 0.05 were considered statistically significant.
UNASSIGNED: Overall, there was no statistically significant difference in AEs between right and left drains in the periprocedural and postprocedural period (p = 0.832, OR = 0.95 and p = 0.808, OR = 0.93 respectively). When analyzing minor AEs individually, only cholangitis occurred at a higher rate on the right side (p = 0.033, OR = 0.43). There was no statistical difference in the rate of major AEs in the periprocedural period between left and right drains (p = 0.311, OR = 1.37).
UNASSIGNED: Current literature is equivocal when comparing right versus left percutaneous biliary drains. This analysis describes no statistically significant difference in AEs between right and left hepatobiliary drains aside from slightly higher incidence of cholangitis for right sided drains.
摘要：
■确定胆道狭窄患者的右肝或左肝经皮胆道引流放置（PTBD）之间的不良事件（AE）是否存在差异。
■这项回顾性研究包括2004年7月28日至2021年3月30日在一家机构接受PTBD治疗的良性或恶性胆道狭窄患者。357例患者符合纳入标准，77（21.6％）在左侧有PTBD，而280（78.4％）在右侧。收集并分类与初始引流管放置或后续干预期间相关的不良事件。分为围手术期的不良事件包括：手术，感染,出血,和排水失败。术后组的不良事件包括：寒战，导管移位,胆管炎,胆道结石,排水故障,发烧不治疗，和导管泄漏。手术被认为是主要的AE，其余的AE被归类为次要的。使用Logistic回归分析进行统计学分析,并且小于0.05的p值被认为具有统计学意义。
■总的来说，在围手术期和术后期间,左右引流管之间的不良事件发生率差异无统计学意义(分别为p=0.832,OR=0.95和p=0.808,OR=0.93).在单独分析次要AE时，只有右侧的胆管炎发生率较高(p=0.033,OR=0.43)。左右引流围手术期主要AE发生率无统计学差异(p=0.311,OR=1.37)。
■目前的文献在比较右侧和左侧经皮胆道引流时是模棱两可的。该分析描述了右和左肝胆管引流之间的AE没有统计学上的显着差异，除了右侧引流的胆管炎发生率略高。
■这项回顾性研究包括2004年7月28日至2021年3月30日在一家机构接受PTBD治疗的良性或恶性胆道狭窄患者。357例患者符合纳入标准，77（21.6％）在左侧有PTBD，而280（78.4％）在右侧。收集并分类与初始引流管放置或后续干预期间相关的不良事件。分为围手术期的不良事件包括：手术，感染,出血,和排水失败。术后组的不良事件包括：寒战，导管移位,胆管炎,胆道结石,排水故障,发烧不治疗，和导管泄漏。手术被认为是主要的AE，其余的AE被归类为次要的。使用Logistic回归分析进行统计学分析,并且小于0.05的p值被认为具有统计学意义。
■总的来说，在围手术期和术后期间,左右引流管之间的不良事件发生率差异无统计学意义(分别为p=0.832,OR=0.95和p=0.808,OR=0.93).在单独分析次要AE时，只有右侧的胆管炎发生率较高(p=0.033,OR=0.43)。左右引流围手术期主要AE发生率无统计学差异(p=0.311,OR=1.37)。
■目前的文献在比较右侧和左侧经皮胆道引流时是模棱两可的。该分析描述了右和左肝胆管引流之间的AE没有统计学上的显着差异，除了右侧引流的胆管炎发生率略高。
