PDF(Pubmed)
Abstract：
UNASSIGNED: Some research have indicated that Bariatric and metabolic surgery (BMS) can reduce the risk of cardiovascular disease (CVD) among individuals with obesity. However, there are few reports available that focuses on assessing effect of BMS on the risk of CVD in Chinese population using multiple models.
UNASSIGNED: This research aims to assess the function of BMS on the risk of CVD in Chinese patients with obesity using multiple CVD risk models.
UNASSIGNED: We performed a retrospective analysis of the basic data and glycolipid metabolism data preoperatively and postoperatively from patients with obesity at our hospital. Subgroup analysis was carried out according to different surgical procedures. Then, the function of BMS on the risk of CVD in the Chinese population was assessed using four models, including: China-PAR risk model, Framingham risk score (FRS), World Health Organization (WHO) risk model, and Globorisk model.
UNASSIGNED: We enrolled 64 patients, 24 (37.5%) of whom underwent laparoscopic sleeve gastrectomy (LSG) while 40 (62.5%) underwent Roux-en-Y gastric bypass (RYGB). The 10-year CVD risk for patients calculated using the China-PAR risk model decreased from 6.3% preoperatively to 2.0% at 1 year postoperatively and was statistically significantly different. Similarly, the 10-year CVD risk of patients calculated using the FRS, WHO, Global risk model decreased significantly at 1 year postoperatively compared to preoperatively. When the FRS risk model was used to calculate the patients\' 30-year postoperative CVD risk, there was a significant decrease at 1 year after surgery compared to the preoperative period. When employing various models to evaluate the 10-year CVD risk for LSG and RYGB, no statistically significant difference was found in the 1-year postoperative RRR between the procedures.
UNASSIGNED: The CVD risk after BMS was significantly reduced compared to preoperatively. In terms of improving cardiovascular risk, SG and RYGB appear to be equally effective.
UNASSIGNED: This research aims to assess the function of BMS on the risk of CVD in Chinese patients with obesity using multiple CVD risk models.
UNASSIGNED: We performed a retrospective analysis of the basic data and glycolipid metabolism data preoperatively and postoperatively from patients with obesity at our hospital. Subgroup analysis was carried out according to different surgical procedures. Then, the function of BMS on the risk of CVD in the Chinese population was assessed using four models, including: China-PAR risk model, Framingham risk score (FRS), World Health Organization (WHO) risk model, and Globorisk model.
UNASSIGNED: We enrolled 64 patients, 24 (37.5%) of whom underwent laparoscopic sleeve gastrectomy (LSG) while 40 (62.5%) underwent Roux-en-Y gastric bypass (RYGB). The 10-year CVD risk for patients calculated using the China-PAR risk model decreased from 6.3% preoperatively to 2.0% at 1 year postoperatively and was statistically significantly different. Similarly, the 10-year CVD risk of patients calculated using the FRS, WHO, Global risk model decreased significantly at 1 year postoperatively compared to preoperatively. When the FRS risk model was used to calculate the patients\' 30-year postoperative CVD risk, there was a significant decrease at 1 year after surgery compared to the preoperative period. When employing various models to evaluate the 10-year CVD risk for LSG and RYGB, no statistically significant difference was found in the 1-year postoperative RRR between the procedures.
UNASSIGNED: The CVD risk after BMS was significantly reduced compared to preoperatively. In terms of improving cardiovascular risk, SG and RYGB appear to be equally effective.
摘要：
■一些研究表明，减肥和代谢手术（BMS）可以降低肥胖个体患心血管疾病（CVD）的风险。然而,在中国人群中,很少有关于使用多种模型评估BMS对CVD风险的影响的报道.
■本研究旨在使用多种CVD风险模型评估BMS对中国肥胖患者CVD风险的功能。
■我们对我院肥胖患者术前和术后的基本数据和糖脂代谢数据进行了回顾性分析。根据不同的手术方式进行亚组分析。然后，使用四个模型评估了BMS对中国人群心血管疾病风险的作用，包括：中国-PAR风险模型，弗雷明汉风险评分（FRS），世界卫生组织（WHO）风险模型，和Globorisk模型。
■我们招募了64名患者，其中24人（37.5％）接受了腹腔镜袖状胃切除术（LSG），而40人（62.5％）接受了Roux-en-Y胃旁路术（RYGB）。使用China-PAR风险模型计算的患者的10年CVD风险从术前的6.3%下降到术后1年的2.0%，差异有统计学意义。同样，使用FRS计算的患者10年CVD风险，WHO,与术前相比，术后1年全球风险模型显着降低。当FRS风险模型用于计算患者术后30年的CVD风险时，与术前相比,手术后1年有显著下降.当采用各种模型评估LSG和RYGB的10年CVD风险时，两组术后1年RRR无统计学差异.
■与术前相比，BMS术后CVD风险显著降低。在改善心血管风险方面，SG和RYGB似乎同样有效。
■本研究旨在使用多种CVD风险模型评估BMS对中国肥胖患者CVD风险的功能。
■我们对我院肥胖患者术前和术后的基本数据和糖脂代谢数据进行了回顾性分析。根据不同的手术方式进行亚组分析。然后，使用四个模型评估了BMS对中国人群心血管疾病风险的作用，包括：中国-PAR风险模型，弗雷明汉风险评分（FRS），世界卫生组织（WHO）风险模型，和Globorisk模型。
■我们招募了64名患者，其中24人（37.5％）接受了腹腔镜袖状胃切除术（LSG），而40人（62.5％）接受了Roux-en-Y胃旁路术（RYGB）。使用China-PAR风险模型计算的患者的10年CVD风险从术前的6.3%下降到术后1年的2.0%，差异有统计学意义。同样，使用FRS计算的患者10年CVD风险，WHO,与术前相比，术后1年全球风险模型显着降低。当FRS风险模型用于计算患者术后30年的CVD风险时，与术前相比,手术后1年有显著下降.当采用各种模型评估LSG和RYGB的10年CVD风险时，两组术后1年RRR无统计学差异.
■与术前相比，BMS术后CVD风险显著降低。在改善心血管风险方面，SG和RYGB似乎同样有效。
