UNASSIGNED: This was a retrospective analysis of patients who underwent VSRR between 2007 and 2021 at a single center. Kaplan-Meier and log-rank analysis were used to estimate and compare freedom from mortality, progression to >2+ aortic insufficiency (AI), and reoperation between groups (BAV vs TAV). Preoperative and postoperative echocardiographic data were collected and assessed for temporal changes in mixed-effect models.
UNASSIGNED: A total of 185 patients (BAV, n = 52, 28.1%; TAV, n = 133, 71.9%) underwent VSRR. At baseline, BAV patients were younger (42.4 ± 11.6 vs 52.3 ± 12.6 years; P < 0.01) and had more severe AI (47.9% vs 27.0%; P = 0.02). Average cardiopulmonary bypass and cross-clamp times were similar. There were no differences in rates of postoperative complications, intensive care unit or hospital days, or 30-day readmission. TAV patients\' 1-, 5-, and 8-year survival rates were 99.2% [95% CI 97.8-100], 96.7% [93.5-99.9%], and 92.2% [85.6-99.3%], respectively. Overall, there were no differences between groups regarding freedom from mortality (P = 0.18), reoperation (P = 0.51), or recurrent >2+ AI (P = 0.97). .
UNASSIGNED: VSRR can be safely performed on patients with BAV and TAV morphology, yielding similar midterm freedom from mortality, recurrent >2+ AI, and reoperation. This technique should be considered in carefully selected patients with aortic root pathology and BAV anatomy when performed at experienced centers.
■这是对2007年至2021年在单个中心接受VSRR的患者的回顾性分析。Kaplan-Meier和log-rank分析用于估计和比较无死亡率,进展为>2+主动脉瓣关闭不全(AI),组间再手术(BAVvsTAV)。收集术前和术后超声心动图数据,并评估混合效应模型中的时间变化。
■总共185名患者(BAV,n=52,28.1%;TAV,n=133,71.9%)接受VSRR。在基线,BAV患者年龄较小(42.4±11.6vs52.3±12.6岁;P<0.01),AI更严重(47.9%vs27.0%;P=0.02)。平均体外循环和交叉钳夹时间相似。术后并发症发生率无差异,重症监护病房或住院天数,或重新接纳30天。TAV患者\'1-,5-,8年生存率为99.2%[95%CI97.8-100],96.7%[93.5-99.9%],和92.2%[85.6-99.3%],分别。总的来说,在无死亡率方面,组间没有差异(P=0.18),再手术(P=0.51),或复发>2+AI(P=0.97)。.
■VSRR可以安全地对具有BAV和TAV形态的患者进行,产生类似的中期死亡率自由,递归>2+AI,再操作。在经验丰富的中心进行时,应在精心选择的主动脉根部病理学和BAV解剖结构的患者中考虑此技术。