Abstract:
We describe the case of a 19-year-old woman who presented with abdominal pain, vomiting, and a palpable purpuric rash. The patient subsequently developed dysentery and was found to have an infection from Shiga toxin-producing Escherichia coli. The patient also met diagnostic criteria for IgA vasculitis (also known as Henoch Schönlein purpura) but had negative immunofluorescence biopsies of the rash. The patient was treated with steroids and achieved recovery. To our knowledge, this is the first documented case of IgA vasculitis in the setting of an enterohemorrhagic E. coli infection. This case highlights an atypical presentation of IgA vasculitis and the need to include small vessel vasculitis as a differential diagnosis when treating patients of all ages.
摘要:
我们描述了一个19岁女性腹痛的案例,呕吐,还有明显的紫癜性皮疹.该患者随后发展为痢疾,并被发现感染了产志贺毒素的大肠杆菌。患者还符合IgA血管炎(也称为过敏性紫癜)的诊断标准,但皮疹的免疫荧光活检呈阴性。患者接受了类固醇治疗并恢复。据我们所知,这是在肠出血性大肠杆菌感染背景下记录的首例IgA血管炎病例。该病例突出了IgA血管炎的非典型表现,并且在治疗所有年龄段的患者时,需要将小血管血管炎作为鉴别诊断。