Abstract：
BACKGROUND: Internet Gaming Disorder (IGD) is recognized as a mental health condition associated with excessive video gaming, leading to functional impairments. The inclusion of IGD in the DSM-5 has underscored the importance of comprehensively understanding its physiological and psychological effects.
OBJECTIVE: This systematic review aims to analyze and synthesize existing literature on the cardiophysiological and neurophysiological activities of individuals diagnosed with IGD, with a focus on identifying patterns, trends, and implications for clinical practice and future research.
METHODS: A systematic search was conducted in PubMed and Scopus databases to identify relevant studies published up to 2023. The search strategy included terms related to IGD, cardiophysiology, neurophysiology, and relevant measurement techniques. Inclusion criteria encompassed peer-reviewed research articles and clinical trials examining cardiophysiological (e.g., heart rate variability, blood pressure) and neurophysiological (e.g., brain imaging, electroencephalography) parameters in individuals with IGD. Exclusion criteria were applied to ensure methodological rigor and relevance to the research question.
RESULTS: The initial search yielded 1320 papers related to IGD, of which twenty studies met the eligibility criteria and were included in the review. Data extraction and synthesis focused on key cardiophysiological and neurophysiological outcomes observed in individuals with IGD compared to healthy controls. Findings revealed decreased Heart Rate Variability (HRV), increased sympathetic activity, and executive control deficits in IGD individuals based on Electrocardiogram (ECG) recordings and cognitive assessments. Neuroimaging studies demonstrated heightened brain activation in the lateral and prefrontal cortex, altered reward processing, and impulse control mechanisms among IGD subjects. Gender-specific differences were noted, with males exhibiting distinct thalamic activation striatum and decreased Regional Homogeneity (ReHo) in the right Posterior Cingulate (rPCC) compared to females.
CONCLUSIONS: The synthesized evidence indicates a complex interplay between excessive gaming and cardiophysiological/neurophysiological changes, highlighting the need for multidimensional assessments in diagnosing and managing IGD. Implications for clinical practice include early detection using ECG, EEG, and advanced neuroimaging techniques, as well as personalized interventions tailored to individual characteristics and gender-specific differences.
CONCLUSIONS: This systematic review provides a comprehensive overview of the cardiophysiological and neurophysiological activities associated with Internet Gaming Disorder. The findings underscore the need for further research to elucidate underlying mechanisms, develop standardized diagnostic protocols, and optimize targeted interventions for individuals with IGD.
OBJECTIVE: This systematic review aims to analyze and synthesize existing literature on the cardiophysiological and neurophysiological activities of individuals diagnosed with IGD, with a focus on identifying patterns, trends, and implications for clinical practice and future research.
METHODS: A systematic search was conducted in PubMed and Scopus databases to identify relevant studies published up to 2023. The search strategy included terms related to IGD, cardiophysiology, neurophysiology, and relevant measurement techniques. Inclusion criteria encompassed peer-reviewed research articles and clinical trials examining cardiophysiological (e.g., heart rate variability, blood pressure) and neurophysiological (e.g., brain imaging, electroencephalography) parameters in individuals with IGD. Exclusion criteria were applied to ensure methodological rigor and relevance to the research question.
RESULTS: The initial search yielded 1320 papers related to IGD, of which twenty studies met the eligibility criteria and were included in the review. Data extraction and synthesis focused on key cardiophysiological and neurophysiological outcomes observed in individuals with IGD compared to healthy controls. Findings revealed decreased Heart Rate Variability (HRV), increased sympathetic activity, and executive control deficits in IGD individuals based on Electrocardiogram (ECG) recordings and cognitive assessments. Neuroimaging studies demonstrated heightened brain activation in the lateral and prefrontal cortex, altered reward processing, and impulse control mechanisms among IGD subjects. Gender-specific differences were noted, with males exhibiting distinct thalamic activation striatum and decreased Regional Homogeneity (ReHo) in the right Posterior Cingulate (rPCC) compared to females.
CONCLUSIONS: The synthesized evidence indicates a complex interplay between excessive gaming and cardiophysiological/neurophysiological changes, highlighting the need for multidimensional assessments in diagnosing and managing IGD. Implications for clinical practice include early detection using ECG, EEG, and advanced neuroimaging techniques, as well as personalized interventions tailored to individual characteristics and gender-specific differences.
CONCLUSIONS: This systematic review provides a comprehensive overview of the cardiophysiological and neurophysiological activities associated with Internet Gaming Disorder. The findings underscore the need for further research to elucidate underlying mechanisms, develop standardized diagnostic protocols, and optimize targeted interventions for individuals with IGD.
摘要：
背景：互联网游戏障碍（IGD）被认为是与过度视频游戏相关的心理健康状况，导致功能障碍。将IGD纳入DSM-5强调了全面了解其生理和心理影响的重要性。
目的：本系统综述旨在分析和综合现有的关于诊断为IGD的个体的心脏生理和神经生理活动的文献。专注于识别模式，趋势,以及对临床实践和未来研究的影响。
方法：在PubMed和Scopus数据库中进行了系统搜索，以确定截至2023年发表的相关研究。搜索策略包括与IGD相关的术语，心脏生理学,神经生理学，和相关的测量技术。纳入标准包括同行评审的研究文章和检查心脏生理学的临床试验(例如，心率变异性,血压)和神经生理学(例如，脑成像,脑电图）IGD患者的参数。应用排除标准以确保方法的严密性和与研究问题的相关性。
结果：最初的搜索产生了1320篇与IGD相关的论文，其中20项研究符合资格标准，并被纳入审查。与健康对照相比，数据提取和综合集中在IGD患者中观察到的关键心脏生理和神经生理学结果。研究结果显示心率变异性（HRV）降低，增加交感神经活动，基于心电图（ECG）记录和认知评估的IGD个体的执行控制缺陷。神经影像学研究表明，外侧和前额叶皮层的大脑激活增强，改变了奖励处理，IGD受试者之间的冲动控制机制。注意到性别差异，与女性相比，男性表现出明显的丘脑激活纹状体，并且右后扣带回（rPCC）的区域均匀性（ReHo）降低。
结论：综合证据表明过度游戏与心脏生理/神经生理变化之间存在复杂的相互作用，强调在诊断和管理IGD方面需要进行多维评估。对临床实践的影响包括使用ECG进行早期检测，脑电图,和先进的神经成像技术，以及针对个体特征和性别差异的个性化干预措施。
结论：本系统综述提供了与网络游戏障碍相关的心脏生理和神经生理活动的全面概述。这些发现强调了进一步研究以阐明潜在机制的必要性，制定标准化的诊断方案，并优化针对IGD患者的针对性干预措施。
目的：本系统综述旨在分析和综合现有的关于诊断为IGD的个体的心脏生理和神经生理活动的文献。专注于识别模式，趋势,以及对临床实践和未来研究的影响。
方法：在PubMed和Scopus数据库中进行了系统搜索，以确定截至2023年发表的相关研究。搜索策略包括与IGD相关的术语，心脏生理学,神经生理学，和相关的测量技术。纳入标准包括同行评审的研究文章和检查心脏生理学的临床试验(例如，心率变异性,血压)和神经生理学(例如，脑成像,脑电图）IGD患者的参数。应用排除标准以确保方法的严密性和与研究问题的相关性。
结果：最初的搜索产生了1320篇与IGD相关的论文，其中20项研究符合资格标准，并被纳入审查。与健康对照相比，数据提取和综合集中在IGD患者中观察到的关键心脏生理和神经生理学结果。研究结果显示心率变异性（HRV）降低，增加交感神经活动，基于心电图（ECG）记录和认知评估的IGD个体的执行控制缺陷。神经影像学研究表明，外侧和前额叶皮层的大脑激活增强，改变了奖励处理，IGD受试者之间的冲动控制机制。注意到性别差异，与女性相比，男性表现出明显的丘脑激活纹状体，并且右后扣带回（rPCC）的区域均匀性（ReHo）降低。
结论：综合证据表明过度游戏与心脏生理/神经生理变化之间存在复杂的相互作用，强调在诊断和管理IGD方面需要进行多维评估。对临床实践的影响包括使用ECG进行早期检测，脑电图,和先进的神经成像技术，以及针对个体特征和性别差异的个性化干预措施。
结论：本系统综述提供了与网络游戏障碍相关的心脏生理和神经生理活动的全面概述。这些发现强调了进一步研究以阐明潜在机制的必要性，制定标准化的诊断方案，并优化针对IGD患者的针对性干预措施。
