Abstract：
BACKGROUND: Reported prevalence for reamputation in diabetic foot is diverse, risk factors are not clear for minor amputations. This study aims to determine the prevalence for reamputation in diabetic foot from minor amputations and to evaluate associated factors for such outcome.
METHODS: Cross sectional study developed in two hospitals. Patients hospitalized for diabetic foot ulcer (DFU) requiring a minor amputation were included. A descriptive analysis of all variables is presented, as well as prevalence ratios (PR) and a multivariate logistic regression.
RESULTS: 48% prevalence for 15 years. Toes were the most frequent minor amputation that required reamputation and above the knee amputation was the most frequent reamputation level (45%). Variables whose PR was associated to reamputation risk were: smoking history (PR 1.32, CI 95% 1.02 - 1.67, p = 0.03), vascular occlusion in doppler (PR 1.47, CI 95% 1.11 - 1.73, p = 0.01), revascularization (PR 1.73, CI 95% 1.31 - 2.14, p = 0.00002), wagner > 3 (PR 1.75, CI 95% 1.16 - 1.84, p = 0.01) and leucocytosis > 11,000 (PR 1.39, CI 95% 1.07 - 1.68, p = 0.01).Leucocytosis > 11,000, Wagner > 3, vascular occlusion in doppler and revascularization were the variables that best predicted the outcome. Furthermore, leucocytosis was the best variable for predicting reamputation (OR 2.4, CI 95% 1.1 - 5.6, p = 0.04).
CONCLUSIONS: Reamputation prevalence was 48%. The toes were the minor amputation more frequently requiring reamputation and above the knee was the most frequent reamputation level. Risk for reamputation was associated with variables related to vascular compromise and infection.
METHODS: IV.
METHODS: Cross sectional study developed in two hospitals. Patients hospitalized for diabetic foot ulcer (DFU) requiring a minor amputation were included. A descriptive analysis of all variables is presented, as well as prevalence ratios (PR) and a multivariate logistic regression.
RESULTS: 48% prevalence for 15 years. Toes were the most frequent minor amputation that required reamputation and above the knee amputation was the most frequent reamputation level (45%). Variables whose PR was associated to reamputation risk were: smoking history (PR 1.32, CI 95% 1.02 - 1.67, p = 0.03), vascular occlusion in doppler (PR 1.47, CI 95% 1.11 - 1.73, p = 0.01), revascularization (PR 1.73, CI 95% 1.31 - 2.14, p = 0.00002), wagner > 3 (PR 1.75, CI 95% 1.16 - 1.84, p = 0.01) and leucocytosis > 11,000 (PR 1.39, CI 95% 1.07 - 1.68, p = 0.01).Leucocytosis > 11,000, Wagner > 3, vascular occlusion in doppler and revascularization were the variables that best predicted the outcome. Furthermore, leucocytosis was the best variable for predicting reamputation (OR 2.4, CI 95% 1.1 - 5.6, p = 0.04).
CONCLUSIONS: Reamputation prevalence was 48%. The toes were the minor amputation more frequently requiring reamputation and above the knee was the most frequent reamputation level. Risk for reamputation was associated with variables related to vascular compromise and infection.
METHODS: IV.
摘要：
背景：报告的糖尿病足截肢的患病率多种多样，轻微截肢的危险因素尚不清楚.这项研究旨在确定因轻微截肢而导致糖尿病足再截肢的患病率，并评估此类结果的相关因素。
方法：在两家医院开展的横断面研究。包括因糖尿病足溃疡（DFU）而需要轻微截肢的患者。对所有变量进行了描述性分析，以及患病率比（PR）和多变量逻辑回归。
结果：15年的患病率为48%。脚趾是需要重新截肢的最常见的小截肢，膝盖以上的截肢是最常见的截肢水平（45％）。PR与再截肢风险相关的变量为：吸烟史（PR1.32，CI95％1.02-1.67，p=0.03），多普勒血管闭塞（PR1.47，CI95％1.11-1.73，p=0.01），血运重建（PR1.73，CI95%1.31-2.14，p=0.00002），瓦格纳>3（PR1.75，CI95%1.16-1.84，p=0.01）和白细胞增多>11,000（PR1.39，CI95%1.07-1.68，p=0.01）。白细胞增多>11,000，Wagner>3，多普勒血管闭塞和血运重建是最好的预测结果的变量。此外，白细胞增多是预测再截肢的最佳变量(OR2.4,CI95%1.1-5.6,p=0.04).
结论：截肢患病率为48%。脚趾是需要重新截肢的较频繁的小截肢，膝盖以上是最常见的重新截肢水平。再次截肢的风险与血管受损和感染相关变量相关。
方法：IV.
方法：在两家医院开展的横断面研究。包括因糖尿病足溃疡（DFU）而需要轻微截肢的患者。对所有变量进行了描述性分析，以及患病率比（PR）和多变量逻辑回归。
结果：15年的患病率为48%。脚趾是需要重新截肢的最常见的小截肢，膝盖以上的截肢是最常见的截肢水平（45％）。PR与再截肢风险相关的变量为：吸烟史（PR1.32，CI95％1.02-1.67，p=0.03），多普勒血管闭塞（PR1.47，CI95％1.11-1.73，p=0.01），血运重建（PR1.73，CI95%1.31-2.14，p=0.00002），瓦格纳>3（PR1.75，CI95%1.16-1.84，p=0.01）和白细胞增多>11,000（PR1.39，CI95%1.07-1.68，p=0.01）。白细胞增多>11,000，Wagner>3，多普勒血管闭塞和血运重建是最好的预测结果的变量。此外，白细胞增多是预测再截肢的最佳变量(OR2.4,CI95%1.1-5.6,p=0.04).
结论：截肢患病率为48%。脚趾是需要重新截肢的较频繁的小截肢，膝盖以上是最常见的重新截肢水平。再次截肢的风险与血管受损和感染相关变量相关。
方法：IV.
