METHODS: We prospectively enrolled consecutive patients from 7/2022-5/2023. We measured TFic, TFdi, and diaphragmatic excursion (DE3) by ultrasound and calculated the TFic/TFdi ratio and diaphragmatic rapid shallow breathing index (D-RSBI4). Receiver-operator characteristic (ROC5) curves evaluated the accuracy of the TFic/TFdi ratio and D-RSBI in predicting weaning failure.
RESULTS: 161 were included in the final analysis, 114 patients (70.8%) were successfully weaned from mechanical ventilation. The TFic/TFdi ratio (AUROC = 0.887 (95% CI: 0.821-0.953)) was superior to the D-RSBI (AUROC = 0.875 (95% CI: 0.807-0.944)) for predicting weaning failure.
CONCLUSIONS: The TFic/TFdi ratio predicted weaning failure with high accuracy and outperformed the D-RSBI.
方法:我们前瞻性招募了2022年7月5日/2023年的连续患者。我们测量了TFIC,TFdi,通过超声和diaphragm肌偏移(DE3),并计算TFic/TFdi比率和diaphragm肌快速浅呼吸指数(D-RSBI4)。接收器-操作员特征(ROC5)曲线评估了TFic/TFdi比率和D-RSBI预测断奶失败的准确性。
结果:161个被纳入最终分析,114例患者(70.8%)成功脱离机械通气。TFic/TFdi比值(AUROC=0.887(95%CI:0.821-0.953))优于D-RSBI(AUROC=0.875(95%CI:0.807-0.944))预测断奶失败。
结论:TFic/TFdi比率可高精度预测断奶失败,优于D-RSBI。