Abstract：
Opioid misuse continues to cause significant harm. To investigate current research, we conducted a scoping literature review of disease spread models of opioid misuse from January 2000 to December 2022. In total, 85 studies were identified and examined for the opioids modeled, model type, data sources used and model calibration and validation. Most of the studies (58%, 49) only modeled heroin; the next largest categories were prescription opioids and unspecified opioids which accounted for 9% (8) each. Most models were theoretical compartmental models (57) or applied compartmental models (21). Previously published research was the most used data source (38), and a majority of the model validation involved the researchers setting initial conditions to verify theoretical results (30). To represent typical opioid use more accurately, multiple opioids need to be incorporated into the disease spread models, and applying different modeling techniques may allow other insights into opioid misuse spread.
摘要：
阿片类药物滥用继续造成重大伤害。为了调查当前的研究，我们对2000年1月至2022年12月阿片类药物滥用的疾病传播模型进行了范围研究文献综述.总的来说,85项研究被确定并检查了阿片类药物模型，型号类型,使用的数据源以及模型校准和验证。大多数研究（58%，49）仅建模海洛因；第二大类别是处方阿片类药物和未指定的阿片类药物，各占9％（8）。大多数模型是理论隔室模型(57)或应用隔室模型(21)。以前发表的研究是最常用的数据源(38)，大多数模型验证涉及研究人员设置初始条件以验证理论结果（30）。为了更准确地代表典型的阿片类药物使用，需要将多种阿片类药物纳入疾病传播模型，和应用不同的建模技术可能允许其他见解阿片类药物滥用传播。
