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Abstract：
BACKGROUND: All the scoring methods for the DLQI miss the moderate impact of the disease on patients, which may underestimate the impact of psoriasis on patients\' quality of life. To improve the accuracy of the assessment of the Dermatology Life Quality Index score (DLQI) for patients with psoriasis, this study proposed and validated a new scoring method, the DLQI-NS, which includes the moderate impact option in the self-assessment of each item in psoriasis patients.
METHODS: A cross-sectional study was conducted in which patients with psoriasis were enrolled. A total of 425 participants completed the DLQI, DLQI-NS and Skindex-16 questionnaires. Reliability, validity, ceiling and floor effects were evaluated of both DLQI and DLQI-NS questionnaires.
RESULTS: About 14.4-32.5% of the patients reported a moderate impact on quality of life. The DLQI-NS allowed 17 more patients (4.0%) to achieve severe disease. The Cronbach\'s alpha coefficient of the DLQI-NS was 0.90, and that of the DLQI was 0.89. The KMO test results for the DLQI-NS and DLQI were 0.927 and 0.916, respectively. One factor was identified for each questionnaire. The items of the DLQI-NS showed an item-total correlation from 0.52 to 0.82, and the DLQI questionnaire\'s item-total correlation ranged from 0.47 to 0.83. The DLQI-NS, DLQI total score and Skindex-16 had Spearman\'s rank correlation coefficients of 0.89 and 0.84, respectively. Both the DLQI-NS and DLQI showed significant moderate correlations with the BSA (0.51 vs. 0.50) and PASI (0.47 vs. 0.46). No ceiling effects were observed for any of the items of both questionnaires.
CONCLUSIONS: The validity and reliability of the DLQI-NS and DLQI were good, but the DLQI-NS was superior to the DLQI. The DLQI-NS is an effective self-assessment tool for assessing quality of life in psoriasis patients.
METHODS: A cross-sectional study was conducted in which patients with psoriasis were enrolled. A total of 425 participants completed the DLQI, DLQI-NS and Skindex-16 questionnaires. Reliability, validity, ceiling and floor effects were evaluated of both DLQI and DLQI-NS questionnaires.
RESULTS: About 14.4-32.5% of the patients reported a moderate impact on quality of life. The DLQI-NS allowed 17 more patients (4.0%) to achieve severe disease. The Cronbach\'s alpha coefficient of the DLQI-NS was 0.90, and that of the DLQI was 0.89. The KMO test results for the DLQI-NS and DLQI were 0.927 and 0.916, respectively. One factor was identified for each questionnaire. The items of the DLQI-NS showed an item-total correlation from 0.52 to 0.82, and the DLQI questionnaire\'s item-total correlation ranged from 0.47 to 0.83. The DLQI-NS, DLQI total score and Skindex-16 had Spearman\'s rank correlation coefficients of 0.89 and 0.84, respectively. Both the DLQI-NS and DLQI showed significant moderate correlations with the BSA (0.51 vs. 0.50) and PASI (0.47 vs. 0.46). No ceiling effects were observed for any of the items of both questionnaires.
CONCLUSIONS: The validity and reliability of the DLQI-NS and DLQI were good, but the DLQI-NS was superior to the DLQI. The DLQI-NS is an effective self-assessment tool for assessing quality of life in psoriasis patients.
摘要：
背景：DLQI的所有评分方法都忽略了疾病对患者的中度影响，这可能低估了银屑病对患者生活质量的影响。提高银屑病患者皮肤病生活质量指数评分(DLQI)评估的准确性,本研究提出并验证了一种新的评分方法，DLQI-NS，其中包括银屑病患者每个项目的自我评估中的中度影响选项。
方法：进行一项横断面研究，纳入银屑病患者。共有425名参与者完成了DLQI，DLQI-NS和Skindex-16问卷。可靠性,有效性，对DLQI和DLQI-NS问卷的上限和下限效应进行了评估。
结果：约14.4-32.5%的患者报告对生活质量有中等影响。DLQI-NS允许另外17名患者(4.0%)达到严重疾病。DLQI-NS的Cronbachα系数为0.90，DLQI的Cronbachα系数为0.89。DLQI-NS和DLQI的KMO测试结果分别为0.927和0.916。每个问卷都确定了一个因素。DLQI-NS的项目总相关性为0.52至0.82，DLQI问卷的项目总相关性为0.47至0.83。DLQI-NS，DLQI总分和Skindex-16的Spearman等级相关系数分别为0.89和0.84。DLQI-NS和DLQI与BSA均显示出显着的中等相关性（0.51vs.0.50）和PASI（0.47vs.0.46)。两项问卷的任何一项均未观察到上限效应。
结论：DLQI-NS和DLQI的效度和信度良好，但DLQI-NS优于DLQI。DLQI-NS是评估银屑病患者生活质量的有效自我评估工具。
方法：进行一项横断面研究，纳入银屑病患者。共有425名参与者完成了DLQI，DLQI-NS和Skindex-16问卷。可靠性,有效性，对DLQI和DLQI-NS问卷的上限和下限效应进行了评估。
结果：约14.4-32.5%的患者报告对生活质量有中等影响。DLQI-NS允许另外17名患者(4.0%)达到严重疾病。DLQI-NS的Cronbachα系数为0.90，DLQI的Cronbachα系数为0.89。DLQI-NS和DLQI的KMO测试结果分别为0.927和0.916。每个问卷都确定了一个因素。DLQI-NS的项目总相关性为0.52至0.82，DLQI问卷的项目总相关性为0.47至0.83。DLQI-NS，DLQI总分和Skindex-16的Spearman等级相关系数分别为0.89和0.84。DLQI-NS和DLQI与BSA均显示出显着的中等相关性（0.51vs.0.50）和PASI（0.47vs.0.46)。两项问卷的任何一项均未观察到上限效应。
结论：DLQI-NS和DLQI的效度和信度良好，但DLQI-NS优于DLQI。DLQI-NS是评估银屑病患者生活质量的有效自我评估工具。
