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Abstract：
BACKGROUND: Salivary gland-type lung carcinomas are uncommon neoplasms of the lung, representing less than 1% of all lung tumors. The two most common among them are adenoid cystic carcinoma and mucoepidermoid carcinoma. Although they usually have an indolent behavior, adenoid cystic carcinomas can be more aggressive, with 5-year survival as low as 55%. Very few cases are reported in literature. We report a similar rare case of salivary gland type lung carcinoma that presented for the first time with unilateral opacification of left hemithorax.
METHODS: A 38-year-old man of North Indian origin, who was a a nonsmoker, presented with complaints of shortness of breath and cough for 1 year, which has increased in the last 2 months and was associated with significant weight loss. A frontal radiograph of the chest and computed tomography of the chest were performed, which showed a mass in the left upper lobe of the lung with its epicenter in the left main bronchus. A bronchoscopic guided biopsy was performed, and histopathology confirmed the diagnosis of lung carcinoma of salivary gland type (adenoid cystic carcinoma). There was invasion of major vessels, hence the patient was offered and started on palliative management instead of surgical treatment. In spite of palliative management of two cycles of chemotherapy and radiotherapy, the patient succumbed to the disease within 2 months from the time of diagnosis.
CONCLUSIONS: Lung carcinoma of the salivary gland type (especially adenoid cystic carcinoma) usually presents at a later stage. The resectability of the tumor depends on the involvement of the surrounding major vessels. Interestingly, these cancers have no association with smoking. The prognosis depends on the extent of the disease at the time of diagnosis. Hence, imaging plays a major role in deciding the further plan of management.
METHODS: A 38-year-old man of North Indian origin, who was a a nonsmoker, presented with complaints of shortness of breath and cough for 1 year, which has increased in the last 2 months and was associated with significant weight loss. A frontal radiograph of the chest and computed tomography of the chest were performed, which showed a mass in the left upper lobe of the lung with its epicenter in the left main bronchus. A bronchoscopic guided biopsy was performed, and histopathology confirmed the diagnosis of lung carcinoma of salivary gland type (adenoid cystic carcinoma). There was invasion of major vessels, hence the patient was offered and started on palliative management instead of surgical treatment. In spite of palliative management of two cycles of chemotherapy and radiotherapy, the patient succumbed to the disease within 2 months from the time of diagnosis.
CONCLUSIONS: Lung carcinoma of the salivary gland type (especially adenoid cystic carcinoma) usually presents at a later stage. The resectability of the tumor depends on the involvement of the surrounding major vessels. Interestingly, these cancers have no association with smoking. The prognosis depends on the extent of the disease at the time of diagnosis. Hence, imaging plays a major role in deciding the further plan of management.
摘要：
背景：涎腺型肺癌是罕见的肺部肿瘤，占所有肺部肿瘤的不到1%。其中最常见的两种是腺样囊性癌和粘液表皮样癌。虽然他们通常有懒惰的行为，腺样囊性癌可能更具侵袭性，5年生存率低至55%。文献中报道的病例很少。我们报告了类似的唾液腺型肺癌罕见病例，该病例首次出现左半胸单侧混浊。
方法：一名38岁的北印度裔男子，他是一个不吸烟的人，出现呼吸急促和咳嗽1年的投诉，在过去2个月中有所增加，并与显着的体重减轻有关。进行了胸部的额叶X光片和胸部的计算机断层扫描，显示左肺上叶有肿块，其中心位于左主支气管。进行了支气管镜引导活检，病理证实诊断为涎腺型肺癌（腺样囊性癌）。主要船只入侵，因此，患者被提供并开始接受姑息治疗，而不是手术治疗。尽管化疗和放疗两个周期的姑息治疗，患者在诊断后2个月内死于该疾病。
结论：涎腺型肺癌（尤其是腺样囊性癌）通常在晚期出现。肿瘤的可切除性取决于周围主要血管的受累。有趣的是,这些癌症与吸烟无关。预后取决于诊断时的疾病程度。因此，影像学在决定进一步的管理计划中起着重要作用。
方法：一名38岁的北印度裔男子，他是一个不吸烟的人，出现呼吸急促和咳嗽1年的投诉，在过去2个月中有所增加，并与显着的体重减轻有关。进行了胸部的额叶X光片和胸部的计算机断层扫描，显示左肺上叶有肿块，其中心位于左主支气管。进行了支气管镜引导活检，病理证实诊断为涎腺型肺癌（腺样囊性癌）。主要船只入侵，因此，患者被提供并开始接受姑息治疗，而不是手术治疗。尽管化疗和放疗两个周期的姑息治疗，患者在诊断后2个月内死于该疾病。
结论：涎腺型肺癌（尤其是腺样囊性癌）通常在晚期出现。肿瘤的可切除性取决于周围主要血管的受累。有趣的是,这些癌症与吸烟无关。预后取决于诊断时的疾病程度。因此，影像学在决定进一步的管理计划中起着重要作用。
