Abstract：
The prognosis of patients with decompensated cirrhosis is poor, with significantly increased liver-related mortality rates. With the rising tide of decompensated cirrhosis associated with metabolic dysfunction-associated steatotic liver disease (MASLD), the role of metabolic bariatric surgery (MBS) in achieving hepatic recompensation is garnering increasing attention. However, the complexity of preoperative assessment, the risk of postoperative disease recurrence, and the potential for patients to experience surgical complications of the MBS present challenges. In this opinion article we analyze the potential of MBS to induce recompensation in MASLD-related cirrhosis, discuss the mechanisms by which MBS may affect recompensation, and compare the characteristics of different MBS procedures; we highlight the therapeutic potential of MBS in MASLD-related cirrhosis recompensation and advocate for research in this complex area.
摘要：
失代偿期肝硬化患者预后差,与肝脏相关的死亡率显着增加。随着与代谢功能障碍相关的脂肪变性肝病（MASLD）相关的失代偿期肝硬化的兴起，代谢减重手术(MBS)在实现肝脏再补偿方面的作用日益受到重视.然而,术前评估的复杂性，术后疾病复发的风险，以及患者经历MBS手术并发症的可能性面临挑战。在这篇观点文章中，我们分析了MBS在MASLD相关肝硬化中诱导再补偿的潜力，讨论MBS可能影响补偿的机制，并比较不同MBS程序的特点;我们强调MBS在MASLD相关肝硬化再补偿中的治疗潜力，并倡导在这一复杂领域的研究。
