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Abstract：
BACKGROUND: This study aims to investigate relative peripheral refractive (RPR) characteristics in children with non-amblyopic myopic anisometropia and explore potential associations between relative peripheral refractive errors (RPRE) and myopia.
METHODS: Relative peripheral refractive errors were assessed in 64 children diagnosed with non-amblyopic myopic anisometropia utilizing multispectral refraction topography (MRT). Two eyes of each patient were divided into into the more myopia eyes group (ME) and the fellow eyes group (FE). Evaluated parameters encompassed total defocus values (TRDV), defocus values at eccentricities spanning 0 to 15 degrees (RDV-15), 0 to 30 degrees (RDV-30), 0 to 45 degrees (RDV-45), as well as superior (RDV-S), inferior (RDV-I), temporal (RDV-T), and nasal (RDV-N) positions.
RESULTS: The study revealed a noteworthy contrast in TRDV values between Group ME (0.52 ± 0.36) and Group FE (0.17 ± 0.41), with a substantial significance (P < 0.0001). While no significant RDV-15 difference emerged between Group ME (0.01 ± 0.05) and Group FE (-0.01 ± 0.07) (P > 0.05), a meaningful RDV-30 difference existed between Group ME (0.11 ± 0.14) and Group FE (0.03 ± 0.19) (P = 0.0017). A significant discrepancy in RDV-45 was also observed between Group ME (0.39 ± 0.29) and Group FE (0.13 ± 0.34) (P < 0.001). Notably, RDV-I and RDV-T positions demonstrated marked differences between Group ME and Group FE (P < 0.0001), whereas no significant disparity was noted in RDV-S and RDV-N positions (P > 0.05).
CONCLUSIONS: Eyes exhibiting greater myopia manifested more hyperopic peripheral defocus in the context of anisometropia. MRT as a novel ophthalmic evaluation technique, holds promising potential for broader clinical applications in the future.
METHODS: Relative peripheral refractive errors were assessed in 64 children diagnosed with non-amblyopic myopic anisometropia utilizing multispectral refraction topography (MRT). Two eyes of each patient were divided into into the more myopia eyes group (ME) and the fellow eyes group (FE). Evaluated parameters encompassed total defocus values (TRDV), defocus values at eccentricities spanning 0 to 15 degrees (RDV-15), 0 to 30 degrees (RDV-30), 0 to 45 degrees (RDV-45), as well as superior (RDV-S), inferior (RDV-I), temporal (RDV-T), and nasal (RDV-N) positions.
RESULTS: The study revealed a noteworthy contrast in TRDV values between Group ME (0.52 ± 0.36) and Group FE (0.17 ± 0.41), with a substantial significance (P < 0.0001). While no significant RDV-15 difference emerged between Group ME (0.01 ± 0.05) and Group FE (-0.01 ± 0.07) (P > 0.05), a meaningful RDV-30 difference existed between Group ME (0.11 ± 0.14) and Group FE (0.03 ± 0.19) (P = 0.0017). A significant discrepancy in RDV-45 was also observed between Group ME (0.39 ± 0.29) and Group FE (0.13 ± 0.34) (P < 0.001). Notably, RDV-I and RDV-T positions demonstrated marked differences between Group ME and Group FE (P < 0.0001), whereas no significant disparity was noted in RDV-S and RDV-N positions (P > 0.05).
CONCLUSIONS: Eyes exhibiting greater myopia manifested more hyperopic peripheral defocus in the context of anisometropia. MRT as a novel ophthalmic evaluation technique, holds promising potential for broader clinical applications in the future.
摘要：
背景：本研究旨在调查非弱视近视性屈光参差儿童的相对周边屈光不正（RPR）特征，并探讨相对周边屈光不正（RPRE）与近视之间的潜在关联。
方法：对64例诊断为非弱视近视性屈光参差的儿童，利用多光谱屈光地形图（MRT）评估了相对周边屈光不正。将每位患者的两只眼睛分为近视眼组（ME）和对眼组（FE）。评估参数包括总散焦值(TRDV)，偏心率在0到15度范围内的散焦值（RDV-15），0到30度（RDV-30），0到45度（RDV-45），以及优越的（RDV-S），劣质（RDV-I），时间（RDV-T），和鼻（RDV-N）位置。
结果：研究显示，ME组（0.52±0.36）和FE组（0.17±0.41）之间的TRDV值存在显著差异，具有实质性意义(P<0.0001)。而ME组(0.01±0.05)与FE组(-0.01±0.07)之间RDV-15无显著性差异(P>0.05),在ME组(0.11±0.14)和FE组(0.03±0.19)之间存在有意义的RDV-30差异(P=0.0017)。在ME组（0.39±0.29）和FE组（0.13±0.34）之间也观察到RDV-45的显着差异（P<0.001）。值得注意的是,RDV-I和RDV-T位置显示ME组和FE组之间存在显著差异(P<0.0001),而RDV-S和RDV-N位置无明显差异（P>0.05）。
结论：在屈光参差的背景下，表现出更大近视的眼睛表现出更多的远视周围散焦。MRT作为一种新颖的眼科评估技术，在未来更广泛的临床应用中具有广阔的潜力。
方法：对64例诊断为非弱视近视性屈光参差的儿童，利用多光谱屈光地形图（MRT）评估了相对周边屈光不正。将每位患者的两只眼睛分为近视眼组（ME）和对眼组（FE）。评估参数包括总散焦值(TRDV)，偏心率在0到15度范围内的散焦值（RDV-15），0到30度（RDV-30），0到45度（RDV-45），以及优越的（RDV-S），劣质（RDV-I），时间（RDV-T），和鼻（RDV-N）位置。
结果：研究显示，ME组（0.52±0.36）和FE组（0.17±0.41）之间的TRDV值存在显著差异，具有实质性意义(P<0.0001)。而ME组(0.01±0.05)与FE组(-0.01±0.07)之间RDV-15无显著性差异(P>0.05),在ME组(0.11±0.14)和FE组(0.03±0.19)之间存在有意义的RDV-30差异(P=0.0017)。在ME组（0.39±0.29）和FE组（0.13±0.34）之间也观察到RDV-45的显着差异（P<0.001）。值得注意的是,RDV-I和RDV-T位置显示ME组和FE组之间存在显著差异(P<0.0001),而RDV-S和RDV-N位置无明显差异（P>0.05）。
结论：在屈光参差的背景下，表现出更大近视的眼睛表现出更多的远视周围散焦。MRT作为一种新颖的眼科评估技术，在未来更广泛的临床应用中具有广阔的潜力。
