Abstract：
OBJECTIVE: We aimed to assess the frequency, management, and burden of enterococcal-related vascular graft infection.
METHODS: From 2008 to 2021, data regarding all episodes of vascular graft infections initially managed or secondarily referred to our referral center were prospectively collected. We described the history and management of the infection, depending on the type of prosthesis used.
RESULTS: The frequency of enterococcal-related vascular graft infections was 29/249 (12 %). Most of them were early infections (22/29, 76 %). Infections were polymicrobial (26/29, 90 %), mostly associated with Enterobacterales. Among patients with positive blood cultures, 7/8 (88 %) involved enterococci. Patients with enterococcal-related vascular graft infections were mainly (22/29, 76 %) treated with an association of antibiotics. Mortality and relapse occurred in 28 % and 7 % respectively of the cases.
CONCLUSIONS: Enterococcal-related vascular graft infections occurred in patients with comorbidities, during the early period following surgery and were more frequent in cases of intra-cavitary prosthesis. Their potential virulence needs to be considered, especially in polymicrobial infections.
METHODS: From 2008 to 2021, data regarding all episodes of vascular graft infections initially managed or secondarily referred to our referral center were prospectively collected. We described the history and management of the infection, depending on the type of prosthesis used.
RESULTS: The frequency of enterococcal-related vascular graft infections was 29/249 (12 %). Most of them were early infections (22/29, 76 %). Infections were polymicrobial (26/29, 90 %), mostly associated with Enterobacterales. Among patients with positive blood cultures, 7/8 (88 %) involved enterococci. Patients with enterococcal-related vascular graft infections were mainly (22/29, 76 %) treated with an association of antibiotics. Mortality and relapse occurred in 28 % and 7 % respectively of the cases.
CONCLUSIONS: Enterococcal-related vascular graft infections occurred in patients with comorbidities, during the early period following surgery and were more frequent in cases of intra-cavitary prosthesis. Their potential virulence needs to be considered, especially in polymicrobial infections.
摘要：
目的：我们旨在评估频率，管理,以及肠球菌相关血管移植物感染的负担。
方法：从2008年到2021年，前瞻性收集了最初治疗或二次转诊到我们转诊中心的所有血管移植物感染发作的数据。我们描述了感染的历史和管理，取决于所用假体的类型。
结果：肠球菌相关性血管移植物感染的频率为29/249（12%）。其中大多数是早期感染（22/29，76％）。感染是多微生物（26/29，90%），主要与肠杆菌有关。在血培养阳性的患者中，7/8（88%）涉及肠球菌。肠球菌相关血管移植物感染的患者主要（22/29，76％）使用抗生素联合治疗。死亡和复发分别发生在28％和7％的病例中。
结论：肠球菌相关性血管移植物感染发生在有合并症的患者中，在手术后的早期，在腔内假体的病例中更为常见。它们潜在的毒力需要考虑,尤其是在多微生物感染中。
方法：从2008年到2021年，前瞻性收集了最初治疗或二次转诊到我们转诊中心的所有血管移植物感染发作的数据。我们描述了感染的历史和管理，取决于所用假体的类型。
结果：肠球菌相关性血管移植物感染的频率为29/249（12%）。其中大多数是早期感染（22/29，76％）。感染是多微生物（26/29，90%），主要与肠杆菌有关。在血培养阳性的患者中，7/8（88%）涉及肠球菌。肠球菌相关血管移植物感染的患者主要（22/29，76％）使用抗生素联合治疗。死亡和复发分别发生在28％和7％的病例中。
结论：肠球菌相关性血管移植物感染发生在有合并症的患者中，在手术后的早期，在腔内假体的病例中更为常见。它们潜在的毒力需要考虑,尤其是在多微生物感染中。
