Abstract：
Antimicrobial resistance (AMR) has emerged as a critical global health challenge. However, the significance of AMR is not limited to humans and domestic animals but extends to wildlife and the environment. Based on the analysis of more than 200 peer-reviewed papers, this review provides comprehensive and current insights into the detection of clinically significant antimicrobial resistant bacteria and resistance genes in wild mammals, birds and reptiles worldwide. The review also examines the overlooked roles of wildlife in AMR emergence and transmission. In wildlife, AMR is potentially driven by anthropogenic activity, agricultural and environmental factors, as well as natural evolution. This review highlights the significance of AMR surveillance in wildlife, identifies species and geographic foci and gaps, and finally demonstrates the value of multifaceted One Health strategies if we are to curtail further escalation of AMR globally.
摘要：
抗菌素耐药性(AMR)已成为一个关键的全球卫生挑战。然而,AMR的意义不仅限于人类和家畜，还延伸到野生动物和环境。根据对200多篇同行评议论文的分析，这篇综述提供了对野生哺乳动物中临床上重要的抗微生物抗性细菌和抗性基因的检测的全面和最新的见解，全世界的鸟类和爬行动物。这篇综述还研究了野生动物在AMR出现和传播中被忽视的作用。在野生动物中，AMR可能是由人为活动驱动的，农业和环境因素，以及自然进化。这篇综述强调了野生动物AMR监测的重要性，确定物种和地理焦点和差距，最后证明了如果我们要遏制全球AMR的进一步升级，多方面的一个健康战略的价值。
