Abstract：
As a kind of commonly-used synthetic materials for many pesticides, thiol compounds, once being leaked, can cause serious harm to the environment and humans. Therefore, the efficient detection of thiol compounds is essential. In this study developed a turn-on fluorescent probe (Cu@Zn-CP) for the highly sensitive fluorescence detection of thiol compounds. The probe was constructed based on a zinc coordination polymer (Zn-CP), whose fluorescence was quenched through the effective doping of Cu2+ ions. After the introduction of methyl thioglycolate (MTC), a rapid fluorescence turn-on response was generated within 90 s with a low detection limit of 23 ppb. Even after being reused for five cycles, the sensor maintains excellent detection performance and demonstrates good recyclability. It can also detect MTC in river water, with a spike recovery rate between 98-103 %. Furthermore, the designed Cu@Zn-CP exhibits good universality for detecting multifarious thiol compounds, including L-cysteine, glutathione, monothioglycerol, and 2-hydroxy-1-ethanethiol. This result provides a potential recyclable fluorescent sensor for thiol compounds.
摘要：
作为多种农药常用的合成材料,硫醇化合物，一旦被泄露，会对环境和人类造成严重危害。因此,巯基化合物的高效检测至关重要。在这项研究中，开发了一种开启荧光探针（Cu@Zn-CP）用于高度敏感的巯基化合物的荧光检测。该探针是基于锌配位聚合物（Zn-CP）构建的，其荧光通过Cu2+离子的有效掺杂而猝灭。引入巯基乙酸甲酯（MTC）后，在90s内产生快速的荧光开启响应，低检测限为23ppb。即使重复使用五个周期，该传感器保持优异的检测性能，并表现出良好的可回收性。它还可以检测河水中的MTC，加标回收率在98-103%之间。此外，设计的Cu@Zn-CP对检测多种硫醇化合物具有良好的通用性，包括L-半胱氨酸,谷胱甘肽,单硫代甘油,和2-羟基-1-乙硫醇。该结果为硫醇化合物提供了潜在的可回收荧光传感器。
