UNASSIGNED: This systematic review and meta-analysis aimed at assessing the efficacy of rehabilitation interventions in improving functioning in fibromyalgia patients.
UNASSIGNED: We conducted a comprehensive literature search of multiple international databases (PubMed, Scopus, and Web of Science) from their inception until November 22nd, 2023. We identified 23 randomized controlled trials (RCTs) assessing multiple rehabilitation strategies. The primary outcome was the Fibromyalgia Impact Questionnaire (FIQ). Study quality was assessed using the Cochrane Risk-of-Bias Tool for Randomized Trials (RoB 2). The study protocol was registered in PROSPERO (CRD42020197666).
UNASSIGNED: Our meta-analysis rehabilitation interventions significantly reduce FIQ scores (MD =-11.74, 95% CI: -16.88 to -6.59, p< 0.0001). Notably, the subgroup analysis showed that different rehabilitation modalities seem to induce different therapeutic responses.
UNASSIGNED: Rehabilitation strategies hold promise in addressing the functional impairments and improving the overall well-being of individuals with fibromyalgia. The study underscores the need for further research to determine the optimal rehabilitation approach and its potential impact on the multilevel disability characterizing patients with fibromyalgia.
■本系统综述和荟萃分析旨在评估康复干预措施在改善纤维肌痛患者功能方面的功效。
■我们对多个国际数据库(PubMed,Scopus,和WebofScience)从成立到11月22日,2023年。我们确定了23项评估多种康复策略的随机对照试验(RCT)。主要结果是纤维肌痛影响问卷(FIQ)。研究质量使用Cochrane偏见风险工具进行随机试验(RoB2)评估。研究方案在PROSPERO(CRD42020197666)中注册。
■我们的荟萃分析康复干预措施显着降低了FIQ评分(MD=-11.74,95%CI:-16.88至-6.59,p<0.0001)。值得注意的是,亚组分析显示,不同的康复方式似乎会引起不同的治疗反应。
■康复策略有望解决患有纤维肌痛的人的功能障碍和改善整体健康状况。该研究强调了需要进一步研究以确定最佳康复方法及其对纤维肌痛患者多水平残疾特征的潜在影响。