Abstract：
OBJECTIVE: The aim of this study was to retrospectively analyze the effect of music therapy on patients with end-stage cancer in hospice care.
METHODS: This retrospective cohort study included 195 patients with end-stage cancer from January 2021 to December 2023. The conventional group comprised patients who received routine hospice care, whereas the combination group comprised those who received routine hospice care and music therapy. The immune indicators, anxiety and depression scores, quality of life scores, and sleep quality scores of both groups were compared before and after management.
RESULTS: Before management, no significant differences were observed in the immune indicators, anxiety and depression scores, quality of life scores, and sleep quality scores between both groups (P > 0.05). However, after management, the immune indicators lymphocytes CD3+ and CD4+ were significantly higher in the combination group than in the conventional group (P < 0.05); in contrast, anxiety and depression and the Pittsburgh Sleep Quality Index scores were lower in the combination group than in the conventional group (P < 0.05). Lastly, the World Health Organization Quality of Life Brief Version scores were significantly higher in all domains in the combination group than in those in the conventional group; furthermore, the degree of decline in the physical, psychological, and social relationship domain scores was smaller in the combination group than in the conventional group (P < 0.05).
CONCLUSIONS: For patients with end-stage cancer, music therapy can improve their immune status, quality of life, and sleep and ameliorate their anxiety and depression.
METHODS: This retrospective cohort study included 195 patients with end-stage cancer from January 2021 to December 2023. The conventional group comprised patients who received routine hospice care, whereas the combination group comprised those who received routine hospice care and music therapy. The immune indicators, anxiety and depression scores, quality of life scores, and sleep quality scores of both groups were compared before and after management.
RESULTS: Before management, no significant differences were observed in the immune indicators, anxiety and depression scores, quality of life scores, and sleep quality scores between both groups (P > 0.05). However, after management, the immune indicators lymphocytes CD3+ and CD4+ were significantly higher in the combination group than in the conventional group (P < 0.05); in contrast, anxiety and depression and the Pittsburgh Sleep Quality Index scores were lower in the combination group than in the conventional group (P < 0.05). Lastly, the World Health Organization Quality of Life Brief Version scores were significantly higher in all domains in the combination group than in those in the conventional group; furthermore, the degree of decline in the physical, psychological, and social relationship domain scores was smaller in the combination group than in the conventional group (P < 0.05).
CONCLUSIONS: For patients with end-stage cancer, music therapy can improve their immune status, quality of life, and sleep and ameliorate their anxiety and depression.
摘要：
目的：本研究的目的是回顾性分析音乐疗法对终末期癌症患者临终关怀的影响。
方法：这项回顾性队列研究包括2021年1月至2023年12月的195例终末期癌症患者。常规组包括接受常规临终关怀的患者，而组合组包括接受常规临终关怀和音乐疗法的患者.免疫指标,焦虑和抑郁评分，生活质量分数，比较两组患者管理前后的睡眠质量评分。
结果：在管理之前，免疫指标无显著差异,焦虑和抑郁评分，生活质量分数，两组睡眠质量评分比较(P>0.05)。然而,在管理之后，联合组淋巴细胞CD3+、CD4+免疫指标明显高于常规组(P<0.05);联合组焦虑抑郁情绪和匹兹堡睡眠质量指数评分均低于常规组(P<0.05)。最后,世界卫生组织生活质量简报版得分在组合组中的所有领域均明显高于常规组；此外，身体素质下降的程度，心理,联合组社会关系领域得分小于常规组(P<0.05)。
结论：对于终末期癌症患者，音乐疗法可以改善他们的免疫状态，生活质量,和睡眠和改善他们的焦虑和抑郁。
方法：这项回顾性队列研究包括2021年1月至2023年12月的195例终末期癌症患者。常规组包括接受常规临终关怀的患者，而组合组包括接受常规临终关怀和音乐疗法的患者.免疫指标,焦虑和抑郁评分，生活质量分数，比较两组患者管理前后的睡眠质量评分。
结果：在管理之前，免疫指标无显著差异,焦虑和抑郁评分，生活质量分数，两组睡眠质量评分比较(P>0.05)。然而,在管理之后，联合组淋巴细胞CD3+、CD4+免疫指标明显高于常规组(P<0.05);联合组焦虑抑郁情绪和匹兹堡睡眠质量指数评分均低于常规组(P<0.05)。最后,世界卫生组织生活质量简报版得分在组合组中的所有领域均明显高于常规组；此外，身体素质下降的程度，心理,联合组社会关系领域得分小于常规组(P<0.05)。
结论：对于终末期癌症患者，音乐疗法可以改善他们的免疫状态，生活质量,和睡眠和改善他们的焦虑和抑郁。
