关键词: heterogeneity host-pathogen single cell virology virus

来  源:   DOI:10.1128/jvi.01273-23

Abstract:
Across a rich 70-year history, single-cell virology has revealed the impact of host and pathogen heterogeneity during virus infections. Recent technological innovations have enabled higher-resolution analyses of cellular and viral heterogeneity. Furthermore, single-cell analysis has revealed extreme phenotypes and provided additional insights into host-pathogen dynamics. Using a single-cell approach to explore fundamental virology questions, contemporary researchers have contributed to a revival of interest in single-cell virology with increased insights and enthusiasm.
摘要:
在丰富的70年历史中,单细胞病毒学揭示了病毒感染过程中宿主和病原体异质性的影响.最近的技术创新使细胞和病毒异质性的高分辨率分析。此外,单细胞分析揭示了极端的表型,并提供了对宿主-病原体动力学的更多见解。使用单细胞方法探索基本的病毒学问题,当代研究人员通过增加的见解和热情,为恢复对单细胞病毒学的兴趣做出了贡献。
公众号