关键词: C-reactive protein fatigue generalized estimating equations nurse-led case management pain rheumatoid arthritis

来  源:   DOI:10.3389/fmed.2024.1373639   PDF(Pubmed)

Abstract:
UNASSIGNED: Rheumatoid arthritis (RA) is a chronic disease and may worsen over time. Today, nurse-led case management (NLCM) has been recommended to improve clinical outcomes for chronic disease patients, yet little is known regarding its impact on pain, fatigue, and C-reactive protein (CRP) among RA patients. We aimed to explore this issue among such groups via a two-group pre- and post-test approach.
UNASSIGNED: All subjects were recruited from one hospital in Taiwan from January 2017 to June 2018 and assigned to either a 6-month NLCM program in addition to usual care or to a control group that received usual care only. All of them were followed for 2 years. Outcomes of interests were compared at four time points: baseline, the third day after NLCM completion, and at 6 and 24 months after NLCM. Effects between them were tested using the generalized estimating equations (GEE) model after adjusting for differences at baseline.
UNASSIGNED: A total of 50 patients in the NLCM group and 46 in the control group were recruited for data analysis. Results from the GEE model indicated that integrating NLCM into conventional care benefited patients in decreasing levels of pain and fatigue, as well as CRP value. These improvements were still observed for 2 years after NLCM.
UNASSIGNED: NLCM was shown to be helpful in lowering pain, fatigue, and CRP, which implies that NLCM may be a reference in the provision of tailored care for those affected by rheumatism.
摘要:
类风湿性关节炎(RA)是一种慢性疾病,随着时间的推移可能会恶化。今天,护士主导的病例管理(NLCM)已被推荐用于改善慢性病患者的临床结果,然而,人们对它对疼痛的影响知之甚少,疲劳,RA患者的C反应蛋白(CRP)。我们旨在通过两组测试前和测试后的方法在这些群体中探索这个问题。
所有受试者均于2017年1月至2018年6月从台湾一家医院招募,除常规护理外,还被分配到6个月的NLCM计划或仅接受常规护理的对照组。他们都被跟踪了2年。在四个时间点比较了兴趣的结果:基线,NLCM完成后的第三天,以及NLCM后6个月和24个月。在调整基线差异后,使用广义估计方程(GEE)模型测试了它们之间的影响。
纳入NLCM组50例患者和对照组46例患者进行数据分析。GEE模型的结果表明,将NLCM纳入常规护理有利于降低患者的疼痛和疲劳程度,以及CRP值。这些改善在NLCM后2年内仍被观察到。
NLCM被证明有助于减轻疼痛,疲劳,CRP,这意味着NLCM可能是为风湿病患者提供量身定制护理的参考。
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