PDF(Pubmed)
Abstract：
Primary mantle cell lymphoma (MCL) in the gastrointestinal tract is rare, accounting for 4-9% of all reported cases of gastrointestinal non-Hodgkin lymphoma. Furthermore, involvement of the entire gastrointestinal tract in MCL is rare. The present report describes an example of MCL characterized by numerous diffuse polypoid lesions along the whole digestive tract. In particular, there was a focus on the endoscopic presentation of the digestive tract. The patient initially received a treatment regimen of rituximab combined with cyclophosphamide, doxorubicin, vincristine and prednisone. After two cycles of treatment, the regimen was changed to rituximab combined with etoposide, oxaliplatin and ifosfamide, with the addition of ibrutinib capsules. Patients with MCL have a poor prognosis; however, complete response can be achieved after treatment.
摘要：
原发性套细胞淋巴瘤（MCL）在胃肠道是罕见的，占所有胃肠道非霍奇金淋巴瘤报告病例的4-9%。此外，MCL的整个胃肠道受累是罕见的。本报告描述了MCL的一个例子，其特征是整个消化道有许多弥漫性息肉样病变。特别是,重点是消化道的内镜表现.患者最初接受利妥昔单抗联合环磷酰胺的治疗方案，阿霉素,长春新碱和泼尼松.经过两个周期的治疗，方案改为利妥昔单抗联合依托泊苷,奥沙利铂和异环磷酰胺，加入依鲁替尼胶囊。MCL患者预后不良；然而，治疗后可达到完全缓解。
