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Abstract：
BACKGROUND: We conducted this investigation to ascertain the dosimetric properties such as the mean and maximum radiation dosage during radiotherapy as well as the extent of radiation exposure to the esophagus. These factors can potentially impact the development of esophagitis in breast cancer patients undergoing supraclavicular radiation.
METHODS: From January to June 2023, an observational study was conducted at Bangabandhu Sheikh Mujib Medical University in Bangladesh. The patients received radiation therapy (40.05 Gy in 15 parts) to the chest wall and supraclavicular node for three weeks. We were able to guess the following from the dose volume histogram (DVH) data: the length of the esophagus in the treatment area (i.e., the size of the esophagus that was visible on the planning CT scan), the maximum dose (Dmax), the mean dose (Dmean), and the volume of the 10Gy (V10Gy) and 20Gy (V20Gy) doses that were given to the esophagus. During radiotherapy, patients were checked on once a week, and the radiotherapy oncology group was used to evaluate and grade esophagitis Results: Patients with left-sided breast cancer showed a higher Dmean, Dmax, and length of the esophagus compared to those with right-sided breast cancer. Specifically, the Dmean was 6.7 (±2.1) Gy, the Dmax was 39.2 (±1.5) Gy, and the length of the esophagus was 6.1 (±1.2) Gy. Patients with left breast cancer had elevated V10Gy and V20Gy values for the esophagus, but the difference was not statistically significant. The incidence of V10Gy for right-sided breast cancer and left-sided breast cancer was 4.2% (±2.6%) and 19.8% (±9.2%), respectively. The V20Gy was 2.4% (±0.9%) for right-sided breast cancer and 13.09% (±5.0%) for left-sided breast cancer Conclusion: In conclusion, there is a strong association between the mean oesophageal dose and radiation to the left supraclavicular region following surgery in women with breast cancer and acute esophagitis. We can reduce esophageal toxicity by prescribing dose restrictions and performing precise delineation of the esophagus.
METHODS: From January to June 2023, an observational study was conducted at Bangabandhu Sheikh Mujib Medical University in Bangladesh. The patients received radiation therapy (40.05 Gy in 15 parts) to the chest wall and supraclavicular node for three weeks. We were able to guess the following from the dose volume histogram (DVH) data: the length of the esophagus in the treatment area (i.e., the size of the esophagus that was visible on the planning CT scan), the maximum dose (Dmax), the mean dose (Dmean), and the volume of the 10Gy (V10Gy) and 20Gy (V20Gy) doses that were given to the esophagus. During radiotherapy, patients were checked on once a week, and the radiotherapy oncology group was used to evaluate and grade esophagitis Results: Patients with left-sided breast cancer showed a higher Dmean, Dmax, and length of the esophagus compared to those with right-sided breast cancer. Specifically, the Dmean was 6.7 (±2.1) Gy, the Dmax was 39.2 (±1.5) Gy, and the length of the esophagus was 6.1 (±1.2) Gy. Patients with left breast cancer had elevated V10Gy and V20Gy values for the esophagus, but the difference was not statistically significant. The incidence of V10Gy for right-sided breast cancer and left-sided breast cancer was 4.2% (±2.6%) and 19.8% (±9.2%), respectively. The V20Gy was 2.4% (±0.9%) for right-sided breast cancer and 13.09% (±5.0%) for left-sided breast cancer Conclusion: In conclusion, there is a strong association between the mean oesophageal dose and radiation to the left supraclavicular region following surgery in women with breast cancer and acute esophagitis. We can reduce esophageal toxicity by prescribing dose restrictions and performing precise delineation of the esophagus.
摘要：
背景：我们进行了这项研究，以确定剂量学特性，例如放疗期间的平均和最大辐射剂量以及食道的辐射暴露程度。这些因素可能会影响接受锁骨上放疗的乳腺癌患者食管炎的发展。
方法：从2023年1月至6月，在孟加拉国的BangabandhuSheikhMujib医科大学进行了一项观察性研究。患者对胸壁和锁骨上淋巴结接受放射治疗（15个部位为40.05Gy），为期三周。我们能够从剂量体积直方图（DVH）数据中猜测以下内容：治疗区域的食道长度（即，在计划CT扫描中可见的食道大小)，最大剂量（Dmax），平均剂量（Dmean），以及给予食道的10Gy（V10Gy）和20Gy（V20Gy）剂量的体积。放疗期间,患者每周检查一次，结果：左侧乳腺癌患者表现出更高的Dmean，Dmax,与右侧乳腺癌患者相比，食道的长度。具体来说,Dmean为6.7（±2.1）Gy，Dmax为39.2(±1.5)Gy,食管长度为6.1(±1.2)Gy。左乳腺癌患者食管V10Gy和V20Gy值升高，但差异无统计学意义。右侧乳腺癌和左侧乳腺癌的V10Gy发生率分别为4.2%(±2.6%)和19.8%(±9.2%),分别。右侧乳腺癌的V20Gy为2.4％（±0.9％），左侧乳腺癌的V20Gy为13.09％（±5.0％）。结论：总之，在患有乳腺癌和急性食管炎的女性患者中,平均食道剂量与手术后左锁骨上区域的放射量有很强的相关性.我们可以通过处方剂量限制和精确描绘食道来减少食道毒性。
方法：从2023年1月至6月，在孟加拉国的BangabandhuSheikhMujib医科大学进行了一项观察性研究。患者对胸壁和锁骨上淋巴结接受放射治疗（15个部位为40.05Gy），为期三周。我们能够从剂量体积直方图（DVH）数据中猜测以下内容：治疗区域的食道长度（即，在计划CT扫描中可见的食道大小)，最大剂量（Dmax），平均剂量（Dmean），以及给予食道的10Gy（V10Gy）和20Gy（V20Gy）剂量的体积。放疗期间,患者每周检查一次，结果：左侧乳腺癌患者表现出更高的Dmean，Dmax,与右侧乳腺癌患者相比，食道的长度。具体来说,Dmean为6.7（±2.1）Gy，Dmax为39.2(±1.5)Gy,食管长度为6.1(±1.2)Gy。左乳腺癌患者食管V10Gy和V20Gy值升高，但差异无统计学意义。右侧乳腺癌和左侧乳腺癌的V10Gy发生率分别为4.2%(±2.6%)和19.8%(±9.2%),分别。右侧乳腺癌的V20Gy为2.4％（±0.9％），左侧乳腺癌的V20Gy为13.09％（±5.0％）。结论：总之，在患有乳腺癌和急性食管炎的女性患者中,平均食道剂量与手术后左锁骨上区域的放射量有很强的相关性.我们可以通过处方剂量限制和精确描绘食道来减少食道毒性。
